Recombinant Human CD40 Ligand/CD40L/TNFSF5 (E. coli)
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Catalog number
C011-1000
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Price
Please ask
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Size
1 mg
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Description
Recombinant Human TNFSF5 is produced by our E.coli expression system and the target gene encoding Met113-Leu261 is expressed.
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Species reactivity
Human
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Origin
Escherichia coli
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Peptide sequence
MQKGDQNPQIAAHVISEASSKTTSVLQWAEKGYYTMSNNLVTLENGKQLTVKRQGLYYIYAQVTFCSNREASSQAPFIASLCLKSPGRFERILLRAANTHSSAKPCGQQSIHLGGVFELQPGASVFVNVTDPSQVSHGTGFTSFGLLKL
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Estimated molecular weight
16,2 kDa
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Protein purity
Greater than 95% as determined by reducing SDS-PAGE.
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Endotoxin level
Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
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Shipping condition
Ambient/Room Temperature
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Package form
Lyophilized from a 0.2 µm filtered solution of 20mM PB, 200mM NaCl, 0.1mM EDTA, pH 7.0.
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Storage conditions
Lyophilized protein should be stored at below -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at below -20°C for 3 months.
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Reconstitution conditions
See included datasheet or contact us for more information.
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UniProt number
P29965
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional description
FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
CD40LG, CD40
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Short name
Recombinant CD40 Ligand/CD40L/TNFSF5 ( )
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
e. coli, Escherichia coli, Recombination of bioactive proteins and longer peptides in Escherichia Coli is done often with His tagging. novo supplies Rec. E. Coli affinity purified or tag purified antigens in 1 quantities or bulk volumes on request.
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Species
E. coli, E. coli, Humans
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Alternative name
Human CD40 Ligand/TNFSF5(E.coli)
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Alternative technique
rec, escherichia
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Alternative to gene target
CD40 molecule, TNF receptor superfamily member 5, Bp50 and CDW40 and p50 and TNFRSF5, CD40 and IDBG-78904 and ENSG00000101017 and 958, ubiquitin protein ligase binding, Extracellular, Cd40 and IDBG-212533 and ENSMUSG00000017652 and 21939, BT.42498 and IDBG-643036 and ENSBTAG00000020736 and 286849
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Gene info
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Identity
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Gene
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Long gene name
CD40 ligand
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1989-06-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Tumor necrosis factor superfamily
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
CD40 molecule
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 5
- CD40 molecule, TNF receptor superfamily member 5
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Synonyms
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GenBank acession
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Locus
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Discovery year
1993-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Tumor necrosis factor receptor superfamily
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VEGA ID
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Locus Specific Databases
Product images
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