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Category
Primary Antibodies
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Long description
Phospholipid-mediated signalling on neurons provokes diverse responses such as neurogenesis, pattern formation and neurite remodelling. A recently uncovered novel set of molecules in the mammalian brain, named plasticity-related genes (PRGs) mediate lipid phosphate phosphatase activity and provide evidence for their involvement in mechanisms of neuronal plasticity.
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Antibody come from
Recombinant enyzme produced in E. coli
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Other description
Provided in 25 mM Tris-HCl, 75 mM NaCl, pH 8.0, 0.05% Tween, 5 mM DTT and 50% glycerol. Antigen Immunoaffiinity Purification
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Clone
Polyclonal
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Antigen antibody binding interaction
Rabbit anti Lipid Phosphate Phosphatase Related Protein 3 Antibody
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Antibody is raised in
Rabbit
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Antibody s reacts with
Human
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Antibody s reacts with these species
This antibody doesn't cross react with other species
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Antibody s specificity
No Data Available
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Application
Western Blot, Enzyme Immunoassay
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Antibody s suited for
1.5 nmole/min/µg of enzyme; Detemined using pNPP; Reaction conditions: 50 µM pNPP, 10 min incubation at 30¼C, 1 µg enzyme.
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Storage
-80ºC
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Relevant references
[1] Takekawa M., Itoh F., Hinoda Y., Arimura Y., Toyota M., Sekiya M., Adachi M., Imai K., Yachi A.; Cloning and characterization of a human cDNA encoding a novel putative cytoplasmic protein-tyrosine-phosphatase.; Biochem. Biophys. Res. Commun. 189:1223-1230(1992)._x000B__x000B_[2] Yang Q., Co D., Sommercorn J., Tonks N.K.;_x000B_ Cloning and expression of PTP-PEST. A novel, human, nontransmembrane protein tyrosine phosphatase.; J. Biol. Chem. 268:6622-6628(1993)._x000B__x000B_[3] Yang Q., Co D., Sommercorn J., Tonks N.K.; pest_x000B_J. Biol. Chem. 268:17650-17650(1993)._x000B__x000B_[4] Schmidt-Arras DE, Bohmer A, Markova B, Choudhary C, Serve H, Bohmer FD. Tyrosine phosphorylation regulates maturation of receptor tyrosine kinases._x000B_Mol Cell Biol. 2005 May;25(9):3690-703. _x000B__x000B_[5] Wisniewska M, Bossenmaier B, Georges G, Hesse F, Dangl M, Kunkele KP, Ioannidis I, Huber R, Engh RA. The 1.1 A resolution crystal structure of the p130cas SH3 domain and ramifications for ligand selectivity. J Mol Biol. 2005 Apr 15;347(5):1005-14. _x000B__x000B_[6] Badour K, Zhang J, Shi F, Leng Y, Collins M, Siminovitch KA. Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation._x000B_J Exp Med. 2004 Jan 5;199(1):99-112. _x000B_
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Protein number
see ncbi
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Warnings
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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About
Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
