Rabbit anti Lipid Phosphate Phosphatase Related Protein 2

• Catalog number
  X1647P
• Price
  Please ask
• Size
  10MinibLots

• Category
  Primary Antibodies
• Long description
  Phospholipid-mediated signalling on neurons provokes diverse responses such as neurogenesis, pattern formation and neurite remodelling. A recently uncovered novel set of molecules in the mammalian brain, named plasticity-related genes (PRGs) mediate lipid phosphate phosphatase activity and provide evidence for their involvement in mechanisms of neuronal plasticity.
• Antibody come from
  Recombinant enyzme produced in E. coli
• Other description
  Provided in 25 mM Tris-HCl, 75 mM NaCl, pH 8.0, 0.05% Tween, 1 mM DTT and 50% glycerol 2 mM EDTA, 10 mM glutathione. Antigen Immunoaffiinity Purification
• Clone
  Polyclonal
• Antigen antibody binding interaction
  Rabbit anti Lipid Phosphate Phosphatase Related Protein 2 Antibody
• Antibody is raised in
  Rabbit
• Antibody s reacts with
  Human
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Western Blot, Enzyme Immunoassay
• Antibody s suited for
  8.0 nmole/min/µg of enzyme; Detemined using pNPP; Reaction conditions: 50 µM pNPP, 20 min incubation at 30¼C, 5 µg enzyme.
• Storage
  -80ºC
• Relevant references
  [1] Ahmad S., Banville D.L., Zhao Z., Fischer E.H., Shen S.H.;_x000B_ A widely expressed human protein-tyrosine phosphatase containing src homology 2 domains.;_x000B_Proc. Natl. Acad. Sci. U.S.A. 90:2197-2201(1993)._x000B__x000B_[2] Vogel W., Lammers R., Huang J., Ullrich A.;_x000B_ Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation.; Science 259:1611-1614(1993)._x000B__x000B_[3] Adachi M., Sekiya M., Miyachi T., Matsuno K., Hinoda Y., Imai K., Yachi A.;_x000B_ Molecular cloning of a novel protein-tyrosine phosphatase SH-PTP3 with sequence similarity to the src-homology region 2.; FEBS Lett. 314:335-339(1992)._x000B__x000B_[4] Bastien L., Ramachandran C., Liu S., Adam M.;_x000B_ Cloning, expression and mutational analysis of SH-PTP2, human protein-tyrosine phosphatase. Biochem. Biophys. Res. Commun. 196:124-133(1993)._x000B__x000B_[5] Freeman R.M. Jr., Plutzky J., Neel B.G.;_x000B_ Identification of a human src homology 2-containing protein-tyrosine-phosphatase: a putative homolog of Drosophila corkscrew.; Proc. Natl. Acad. Sci. U.S.A. 89:11239-11243(1992)._x000B__x000B_[6] Bennett A.M., Tang T.L., Sugimoto S., Walsh C.T., Neel B.G.;_x000B_ Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras. Proc. Natl. Acad. Sci. U.S.A. 91:7335-7339(1994)._x000B__x000B_[7] Salomon A.R., Ficarro S.B., Brill L.M., Brinker A., Phung Q.T., Ericson C., Sauer K., Brock A., Horn D.M., Schultz P.G., Peters E.C.;_x000B_ Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry.; Proc. Natl. Acad. Sci. U.S.A. 100:443-448(2003)._x000B__x000B_[8] Kharitonenkov A., Chen Z., Sures I., Wang H., Schilling J., Ullrich A.;_x000B_ A family of proteins that inhibit signalling through tyrosine kinase receptors.; Nature 386:181-186(1997)._x000B__x000B_[9] Hof P., Pluskey S., Dhe-Paganon S., Eck M.J., Shoelson S.E.;_x000B_ Crystal structure of the tyrosine phosphatase SHP-2.; Cell 92:441-450(1998)._x000B__x000B_[10] Tartaglia M., Mehler E.L., Goldberg R., Zampino G., Brunner H.G., Kremer H., van der Burgt I., Crosby A.H., Ion A., Jeffery S., Kalidas K., Patton M.A., Kucherlapati R.S., Gelb B.D.;_x000B_ Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome.; Nat. Genet. 29:465-468(2001)._x000B_
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• About
  Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  Lipid   Phosphate   Phosphatase   Related   Protein  
• Short name
  Rabbit anti Lipid Phosphate Phosphatase Protein 2
• Technique
  Rabbit, anti, antibody to
• Host
  Rabbit, Rabbits
• Isotype
  not specified
• Label
  unlabeled
• Alternative name
  production species: rabbit antibody to Lipid Phosphate Phosphatase Related Protein 2
• Alternative technique
  rabbit-anti, antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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