Flt1 N-Terminal His Tag - Active Enzyme

• Catalog number
  X1758E
• Price
  Please ask
• Size
  10 μg

• Category
  Proteins & Peptides
• Long description
  Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis._x000B__x000B_Description: Human recombinant Flt1 (FMS-like tyrosine kinase), also known as VEGFR1 (Vascular endothelial growth factor receptor 1), GenBank Accession No. AF063657, a.a. 783-end with N-terminal His tag, MW=67.5 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
• Antibody come from
  Rabbit polyclonal AIM antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human AIM.
• Other description
  Provided as solution in phosphate buffered saline with 0.02% sodium azide.
• Clone
  not specified
• Antigen antibody binding interaction
  Flt1 N-Terminal His Tag - Active Enzyme
• Antibody is raised in
  Sf9 cells
• Antibody s reacts with
  Human
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Antibody s suited for
  AIM antibody can be used for the detection of AIM by Western blot at 1 Ð 2 ug/ml. Optimal concentration should be evaluated by serial dilutions.
• Storage
  -20ºC
• Relevant references
  1)Miyazaki T, Hirokami Y, Matsuhashi N, et al. Increased susceptibility of thymocytes to apoptosis in mice lacking AIM, a novel murine macrophage-derived soluble factor belonging to the scavenger receptor cysteine-rich domain superfamily. J. Exp. Med. 1999; 189:413-22._x000B_2) Biancone L, Bowen MA, Lim A, et al. Identification of a novel inducible cell-surface ligand of CD5 on activated lymphocytes. J. Exp. Med. 1996; 184:811-9._x000B_3) Haruta I, Kato Y, Hashimoto E, et al. Association of AIM, a novel apoptosis inhibitory factor, with hepatitis via supporting macrophage survival and enhancing phagocytic function of macrophages. J. Biol. Chem. 2001; 276:22910-4_x000B_4) Kuwata K, Watanabe H, Jiang S-Y, et al. AIM inhibits apoptosis of T cells and NKT cells in Corynebacterium-induced granuloma formation in mice. Am. J. Path. 2003; 162:837-47.
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
• Conjugation
  histidine

• Gene target
  Flt1   His   Tag   Active  
• Short name
  Flt1 N-Terminal His Tag - Active Enzyme
• Technique
  Enzyme, enzymes, Tags
• Isotype
  not specified
• Label
  unlabeled
• Alternative name
  Flt1 N-Terminal histidine detection labelled - functionnal Enzyme
• Alternative technique
  enzymes

Similar products