WNT3 Antibody

• Catalog number
  F43549-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  WNT3
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the WNT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This WNT3 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P56703
• Purity
  Antigen affinity
• Description
  The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
• Immunogen
  A portion of amino acids 155-184 from the human protein was used as the immunogen for this WNT3 antibody.
• Storage
  Aliquot the WNT3 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  WNT3  
• Gene symbol
  WNT3
• Short name
  Anti-WNT3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to WNT3
• Alternative technique
  antibodies
• Alternative to gene target
  wingless-type MMTV integration site family, member 3, INT4, WNT3 and IDBG-55691 and ENSG00000108379 and 101929777,7473, receptor a this GO nist activity, Extracellular, Wnt3 and IDBG-213058 and ENSMUSG00000000125 and 22415, BT.88369 and IDBG-641199 and ENSBTAG00000016012 and 540753

Gene info

• Identity
  HGNC:12782
• Gene
  WNT3
• Long gene name
  Wnt family member 3
• Synonyms gene
  • INT4
• Synonyms gene name
  • wingless-type MMTV integration site family, member 3
• Synonyms
  • MGC131950
  • MGC138321
  • MGC138323
• Synonyms name
  • WNT-3 proto-oncogene protein
• GenBank acession
  • AY009397
• Locus
  17q21.31-q21.32
• Discovery year
  1989-05-30
• Entrez gene record
  7473
• Pubmed identfication
  • 8244403
• RefSeq identity
  • NM_030753
• Classification
  • Wnt family
• VEGA ID
  OTTHUMG00000178076

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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