TRPV6 Antibody

• Catalog number
  F52629-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  TRPV6
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the TRPV6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This TRPV6 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9H1D0
• Purity
  Antigen affinity
• Description
  Calcium selective cation channel probably involved in Ca(2+) uptake in various tissues, including Ca(2+) reabsorption in intestine. The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both, a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin- dependent mechanism, the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity).
• Immunogen
  This TRPV6 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 352-385 amino acids from the Central region of human TRPV6.
• Storage
  Aliquot the TRPV6 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TRPV6  
• Gene symbol
  TRPV6
• Short name
  Anti-TRPV6
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to TRPV6
• Alternative technique
  antibodies
• Alternative to gene target
  transient receptor potential cation channel, subfamily V, member 6, TRPV6 and IDBG-45160 and ENSG00000165125 and 55503, calmodulin binding, Plasma membranes, Trpv6 and IDBG-140883 and ENSMUSG00000029868 and 64177, TRPV6 and IDBG-636798 and ENSBTAG00000024219 and 614878

Gene info

• Identity
  HGNC:14006
• Gene
  TRPV6
• Long gene name
  transient receptor potential cation channel subfamily V member 6
• Synonyms gene
  • ECAC2
• Synonyms gene name
  • epithelial calcium channel 2
  • transient receptor potential cation channel, subfamily V, member 6
• Synonyms
  • CaT1
• GenBank acession
  • AJ277909
• Locus
  7q34
• Discovery year
  2000-11-24
• Entrez gene record
  55503
• Pubmed identfication
  • 11097838
  • 11549322
  • 16382100
  • 16717058
• RefSeq identity
  • NM_014274
• Classification
  • Transient receptor potential cation channels
  • Ankyrin repeat domain containing
• VEGA ID
  OTTHUMG00000157158

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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