Rabbit Anti Human TRPV6 Antibody-Non-conjugated
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Catalog numberCSB-PA861992LA01HU_100ug
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PricePlease ask
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Size100ug
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Long nameRabbit Antibody against Human TRPV6, Non-conjugated
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Synonym nameTRPV6 Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA, IHC; Recommended dilution: IHC:1:200-1:500
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDQ9H1D0
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant Human Transient receptor potential cation channel subfamily V member 6 protein (620-764AA)
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Immunogen speciesHuman
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AliasTransient receptor potential cation channel subfamily V member 6, TrpV6, CaT-like1, TRPV6, ECAC2
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BackgroundCalcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine (PubMed:11097838, PubMed:11278579, PubMed:11248124 PubMed:15184369, PubMed:23612980). Important for normal Ca(2+) ion homeostasis in the body, including bone and skin (By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification (PubMed:15184369). Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism; the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
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ClonalityPolyclonal antibody
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Shipping and storageTRPV6 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Short name of the antigenTransient receptor potential cation channel subfamily V member 6
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolTRPV6
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Short nameAnti-TRPV6
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesHuman, Humans
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Alternative nameTRPV6 Antibody
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targettransient receptor potential cation channel, subfamily V, member 6, TRPV6 and IDBG-45160 and ENSG00000165125 and 55503, calmodulin binding, Plasma membranes, Trpv6 and IDBG-140883 and ENSMUSG00000029868 and 64177, TRPV6 and IDBG-636798 and ENSBTAG00000024219 and 614878
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Gene info
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Identity
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Gene
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Long gene nametransient receptor potential cation channel subfamily V member 6
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Synonyms gene
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Synonyms gene name
- epithelial calcium channel 2
- transient receptor potential cation channel, subfamily V, member 6
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-11-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Transient receptor potential cation channels
- Ankyrin repeat domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data