TP63 Antibody
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Catalog numberF43397-0.4ML
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PricePlease ask
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Size0.4 ml
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CategoryAntibody
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ConcentrationIn 1X PBS, pH 7.4, with 0.09% sodium azide
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenTP63
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB, ELISA
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Recommended dilutionsWestern blot: 1:1000
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NotesTitration of the TP63 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis TP63 antibodyis to be used only for research purposes and not for diagnostics..
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UniprotQ9H3D4
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PurityAntigen affinity
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DescriptionThis gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.
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ImmunogenA portion of amino acids 651-680 from the human protein was used as the immunogen for this TP63 antibody.
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StorageAliquot the TP63 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolTP63
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Short nameAnti-TP63
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit Ig
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Alternative nameAntibodies to TP63
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Alternative techniqueantibodies
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Alternative to gene targettumor protein p63, AIS and B(p51A) and B(p51B) and EEC3 and KET and LMS and NBP and OFC8 and p40 and p51 and p53CP and p63 and p73H and p73L and RHS and SHFM4 and TP53CP and TP53L and TP73L, TP63 and IDBG-69487 and ENSG00000073282 and 8626, WW domain binding, nuclei, Trp63 and IDBG-150133 and ENSMUSG00000022510 and 22061, TP63 and IDBG-634533 and ENSBTAG00000015460 and 615335
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Gene info
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Identity
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Gene
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Long gene nametumor protein p63
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Synonyms gene
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Synonyms gene name
- tumor protein p73-like
- tumor protein p53-like
- tumor protein p53-competing protein
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-04-18
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data