TLR5 Antibody

• Catalog number
  F44375-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  TLR5
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
• Notes
  Titration of the TLR5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This TLR5 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9JLF7
• Purity
  Purified
• Description
  TLR5, a Type I membrane protein belonging to the Toll-like receptor family, participates in the innate immune response to microbial agents. It also plays a role in mediating detection of bacterial flagellins. TLR5 acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. This protein binds to TIRAP and MyD88 via their respective TIR domains TLR5 is highly expressed in liver, and is detected in lung and at very low levels in most other tissues. The TLR5 gene lies in a locus that is associated with susceptibility to Salmonella. Inbred strains of mice can be classified into 3 categories according to their resistance to infection with S.typhimurium: susceptible (BALB/c, C57BL/6, C3H/He), intermediate (DBA/2, C75L) and resistant (A, CBA). The strain MOLF/Ei is highly susceptible to the infection, has an unique TLR5 haplotype and a lower expression of TRL5.
• Immunogen
  A portion of amino acids 825-856 from the mouse protein was used as the immunogen for this TLR5 antibody.
• Storage
  Aliquot the TLR5 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TLR5  
• Gene symbol
  TLR5
• Short name
  Anti-TLR5
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to TLR5
• Alternative technique
  antibodies
• Alternative to gene target
  toll-like receptor 5, MELIOS and SLE1 and SLEB1 and TIL3, TLR5 and IDBG-106840 and ENSG00000187554 and 7100, protein binding, Plasma membranes, Tlr5 and IDBG-259066 and ENSMUSG00000079164 and 53791, TLR5 and IDBG-648348 and ENSBTAG00000000477 and 444870

Gene info

• Identity
  HGNC:11851
• Gene
  TLR5
• Long gene name
  toll like receptor 5
• Synonyms gene
  • SLEB1
• Synonyms gene name
  • systemic lupus erythematosus susceptibility 1
  • toll-like receptor 5
• Synonyms
  • TIL3
  • FLJ10052
  • MGC126430
  • MGC126431
• Synonyms name
  • Toll/interleukin-1 receptor-like protein 3
• Locus
  1q41
• Discovery year
  1998-06-25
• Entrez gene record
  7100
• Pubmed identfication
  • 9435236
  • 16027372
• RefSeq identity
  • NM_003268
• Classification
  • Toll like receptors
• VEGA ID
  OTTHUMG00000037937

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products