Survivin Antibody
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Catalog numberN1087-100UG
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PricePlease ask
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Size0.1mg
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CategoryAntibody
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Concentration0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
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FormPurified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenSurvivin
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB
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Recommended dilutionsWestern blot: 2-5ug/ml
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NotesProvided assay concentrations are suggestions only, antibody titration may be required for optimal results.
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Added buffer1X Phosphate Buffered Saline (PBS), pH 7.4
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Intented useThis Survivin antibodyis to be used only for research purposes and not for diagnostics..
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Gene ID332
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PurityPurified by protein A Affinity Chromatography
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DescriptionSurvivin, also called BIRC5, is a protein encoded by the human BIRC5 gene. It is a member of the IAP (inhibitor of apoptosis family. Survivin binds to the active form of Caspase-3 and -7, effector or executioner caspases, preventing them from continuing the apoptosis-signaling cascade. Expression is regulated by p53, a regulator of apoptosis-control genes which interacts with the Survivin gene promoter region to repress its expression at the mRNA and protein level.
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ImmunogenA recombinant protein fragment from human Survivin was used as the immunogen for this antibody.
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StorageAliquot the antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolBIRC5
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Short nameAnti-Survivin
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameAntibodies to Survivin
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namebaculoviral IAP repeat containing 5
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Synonyms gene
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Synonyms gene name
- apoptosis inhibitor 4
- baculoviral IAP repeat-containing 5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-06-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Baculoviral IAP repeat containing
- Chromosomal passenger complex
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data