SERPINA3 Antibody

• Catalog number
  R31341
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  SERPINA3
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the SERPINA3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This SERPINA3 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P01011
• Purity
  Antigen affinity
• Description
  Alpha 1-antichymotrypsin, also called serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 or GIG24, is an alpha globulin glycoprotein that is a member of the serpin superfamily. In humans, it is encoded by the SERPINA3 gene. This gene is mapped to 14q32.13. The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimers disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
• Immunogen
  An amino acid sequence from the middle region of human SERPINA3 (EMPFDPQDTHQSRFY) was used as the immunogen for this SERPINA3 antibody.
• Storage
  After reconstitution, the SERPINA3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SERPINA3  
• Gene symbol
  SERPINA3
• Short name
  Anti-SERPINA3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to SERPINA3
• Alternative technique
  antibodies
• Alternative to gene target
  serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3, SERPINA3 and IDBG-18406 and ENSG00000196136 and 12, protein binding, nuclei

Gene info

• Identity
  HGNC:16
• Gene
  SERPINA3
• Long gene name
  serpin family A member 3
• Synonyms gene
  • AACT
• Synonyms gene name
  • alpha-1-antichymotrypsin
  • serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
• Synonyms
  • ACT
• Synonyms name
  • alpha-1 antichymotrypsin
• GenBank acession
  • K01500
• Locus
  14q32.13
• Discovery year
  2001-06-22
• Entrez gene record
  12
• Pubmed identfication
  • 3260956
  • 24172014
• RefSeq identity
  • NM_001085
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000029851

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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