Periostin Antibody

• Catalog number
  R31158
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Periostin
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the Periostin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Periostin antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q62009
• Purity
  Antigen affinity
• Description
  POSTN(Periostin), also known as PN or OSF2, is a protein that in humans is encoded by the POSTN gene. The International Radiation Hybrid Mapping Consortium mapped the POSTN gene to chromosome 13. Gillan et al.(2002) found that purified recombinant PN supported adhesion of ovarian epithelial cells. Shao et al.(2004) found that periostin was overexpressed by the majority of human primary breast cancers examined. Transfected tumor cell lines overexpressing periostin showed accelerated growth and angiogenesis as xenografts in immunocompromised animals. Kuhn et al.(2007) showed that extracellular periostin induced reentry of differentiated mammalian cardiomyocytes into the cell cycle.
• Immunogen
  An amino acid sequence from the N-terminus of mouse Periostin(NSYYDKVLAHSRIRGRDQ) was used as the immunogen for this Periostin antibody (100% rat homology).
• Storage
  After reconstitution, the Periostin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Periostin  
• Gene symbol
  POSTN
• Short name
  Anti-Periostin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Periostin
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16953
• Gene
  POSTN
• Long gene name
  periostin
• Synonyms gene name
  • periostin, osteoblast specific factor
• Synonyms
  • OSF-2
  • PN
  • periostin
• Synonyms name
  • osteoblast specific factor 2
• GenBank acession
  • D13665
• Locus
  13q13.3
• Discovery year
  2004-02-10
• Entrez gene record
  10631
• Pubmed identfication
  • 8363580
  • 12235007
• RefSeq identity
  • NM_006475
• Classification
  • Gla domain containing
• VEGA ID
  OTTHUMG00000016751

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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