Periostin Antibody

• Catalog number
  PA2048-1
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  Periostin
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human, mouse, rat
• Analyses
  WB
• Immunogen
  A synthetic peptide corresponding to a sequence at the C-terminus of human Periostin(811-824aa DTPVRKLQANKKVQ), different from the related mouse sequence by five amino acids, and from the related rat sequence by four amino acids.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the Periostin Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The Periostin Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  POSTN(Periostin), also known as PN or OSF2, is a protein that in humans is encoded by the POSTN gene. The International Radiation Hybrid Mapping Consortium mapped the POSTN gene to chromosome 13. Gillan et al.(2002) found that purified recombinant PN supported adhesion of ovarian epithelial cells. Shao et al.(2004) found that periostin was overexpressed by the majority of human primary breast cancers examined. Transfected tumor cell lines overexpressing periostin showed accelerated growth and angiogenesis as xenografts in immunocompromised animals. Kuhn et al.(2007) showed that extracellular periostin induced reentry of differentiated mammalian cardiomyocytes into the cell cycle.
• Related articles
  1. Gillan, L., Matei, D., Fishman, D. A., Gerbin, C. S., Karlan, B. Y., Chang, D. D. Periostin secreted by epithelial ovarian carcinoma is a ligand for alpha-V-beta-3 and alpha-V-beta-5 integrins and promotes cell motility. Cancer Res. 62: 5358-5364, 2002. 2. Kuhn, B., del Monte, F., Hajjar, R. J., Chang, Y.-S., Lebeche, D., Arab, S., Keating, M. T. Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair. Nature Med. 13: 962-969, 2007. 3. Shao, R., Bao, S., Bai, X., Blanchette, C., Anderson, R. M., Dang, T., Gishizky, M. L., Marks, J. R., Wang, X.-F. Acquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expression. Molec. Cell. Biol. 24: 3992-4003, 2004.
• Gene Name
  POSTN
• Protein Name
  Periostin
• Gene Full Name
  periostin, osteoblast specific factor
• Synonyms
  MGC119510 antibody|MGC119511 antibody|OSF 2 antibody|OSF-2 antibody|OSF2 antibody|Osteoblast specific factor 2(fasciclin I like) antibody|osteoblast specific factor 2(fasciclin I-like) antibody|Osteoblast specific factor 2 antibody|Osteoblast specific factor antibody|Osteoblast-specific factor 2 antibody|PDLPOSTN antibody|Periodontal ligament specific periostin antibody|Periostin antibody|Periostin isoform thy2 antibody|Periostin isoform thy4 antibody|Periostin isoform thy6 antibody|Periostin isoform thy8 antibody|Periostin osteoblast specific factor antibody|PN antibody|POSTN antibody|POSTN_HUMAN antibody|RP11 412K4.1 antibody
• Uniprot ID
  Q15063
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Periostin  
• Gene symbol
  POSTN
• Short name
  Periostin Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Periostin (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16953
• Gene
  POSTN
• Long gene name
  periostin
• Synonyms gene name
  • periostin, osteoblast specific factor
• Synonyms
  • OSF-2
  • PN
  • periostin
• Synonyms name
  • osteoblast specific factor 2
• GenBank acession
  • D13665
• Locus
  13q13.3
• Discovery year
  2004-02-10
• Entrez gene record
  10631
• Pubmed identfication
  • 8363580
  • 12235007
• RefSeq identity
  • NM_006475
• Classification
  • Gla domain containing
• VEGA ID
  OTTHUMG00000016751

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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