p63 Antibody / Tumor protein 63

• Catalog number
  V3367SAF-100UG
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  1 mg/ml in 1X PBS; BSA free, sodium azide free
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  p63 / Tumor protein 63
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens). Others not known. ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  FACS, IF, IHC-P
• Recommended dilutions
  Flow Cytometry: 0.5-1ug/million cells in 0.1ml,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
• Notes
  The optimal dilution of the p63 antibody for each application should be determined by the researcher.
• Intented use
  This p63 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9H3D4
• Purity
  Purified by protein A Affinity Chromatography
• Description
  p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands; however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90%. Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80%. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.
• Immunogen
  Recombinant partial human p53 protein was used as the immunogen for this p63 antibody.
• Storage
  Store the p63 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
• Localization
  Nuclear
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  p63   Tumor   protein  
• Short name
  Anti-p63 / Tumor protein 63
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to p63 / Tumor protein 63
• Alternative technique
  antibodies
• Tissue
  tumor

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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