p62 Antibody SQSTM1 (phospho-S403)

• Catalog number
  F48757-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS pH 7.4 with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  p62 SQSTM1 (phospho-S403)
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  DB, ELISA
• Recommended dilutions
  Dot blot: 1:500
• Notes
  Titration of the p-p62 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This p-p62 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q13501
• Purity
  Antigen affinity
• Description
  This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
• Immunogen
  This p-p62 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS403 of human p62/SQSTM1.
• Storage
  Aliquot the p-p62 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  p62   SQSTM1   phospho-S403  
• Gene symbol
  SQSTM1
• Short name
  Anti-p62 SQSTM1 (phospho-S403)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to p62 SQSTM1 (phospho-S403)
• Alternative technique
  antibodies
• Alternative to gene target
  sequestosome 1, A170 and OSIL and p60 and p62 and p62B and PDB3 and ZIP3, SQSTM1 and IDBG-61811 and ENSG00000161011 and 8878, K63-linked polyubiquitin binding, nuclei, Sqstm1 and IDBG-168358 and ENSMUSG00000015837 and 18412, BT.105440 and IDBG-640935 and ENSBTAG00000015591 and 338045

Gene info

• Identity
  HGNC:11280
• Gene
  SQSTM1
• Long gene name
  sequestosome 1
• Synonyms gene
  • PDB3
  • OSIL
• Synonyms gene name
  • Paget disease of bone 3
  • oxidative stress induced like
• Synonyms
  • p62
  • p60
  • p62B
  • A170
• Synonyms name
  • autophagy receptor p62
• GenBank acession
  • U46751
• Locus
  5q35.3
• Discovery year
  2000-06-13
• Entrez gene record
  8878
• Pubmed identfication
  • 8650207
  • 8551575
• Classification
  • Zinc fingers ZZ-type
• VEGA ID
  OTTHUMG00000150643

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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