MITF Antibody

• Catalog number
  F41536-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  MITF
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IF, FACS, ELISA
• Recommended dilutions
  Western blot: 1:1000-2000,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
• Notes
  Titration of the MITF antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This MITF antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O75030
• Purity
  Antigen affinity
• Description
  This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Immunogen
  A portion of amino acids 1-28 from the human protein was used as the immunogen for this MITF antibody.
• Storage
  Aliquot the MITF antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MITF  
• Gene symbol
  MITF
• Short name
  Anti-MITF
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to MITF
• Alternative technique
  antibodies
• Alternative to gene target
  microphthalmia-associated transcription factor, bHLHe32 and CMM8 and MI and WS2 and WS2A, MITF and IDBG-44086 and ENSG00000187098 and 4286, protein dimerization activity, nuclei, Mitf and IDBG-172461 and ENSMUSG00000035158 and 17342, BT.29882 and IDBG-644985 and ENSBTAG00000006679 and 407219

Gene info

• Identity
  HGNC:7105
• Gene
  MITF
• Long gene name
  melanocyte inducing transcription factor
• Synonyms gene
  • WS2A
  • WS2
• Synonyms gene name
  • Waardenburg syndrome, type 2A
  • microphthalmia-associated transcription factor
  • melanogenesis associated transcription factor
• Synonyms
  • MI
  • bHLHe32
• Synonyms name
  • homolog of mouse microphthalmia
• Locus
  3p13
• Discovery year
  1993-10-27
• Entrez gene record
  4286
• Pubmed identfication
  • 8069297
  • 7874167
  • 7951321
• RefSeq identity
  • NM_198159
• Classification
  • Basic helix-loop-helix proteins
• VEGA ID
  OTTHUMG00000149921
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_776

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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