MITF Antibody

• Catalog number
  bs-1990R
• Price
  Please ask
• Size
  0.1ml

• Long name
  MITF Primary Polyclonal Antibody
• Also known as
  MITF PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  MITF
• Specificity
  This is a highly specific antibody against MITF.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  350-400/526
• Subcellular location
  Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MITF
• Gene ID number
  4286
• Swiss Prot
  O75030
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  MI; WS2; CMM8; WS2A; bHLHe32; Microphthalmia-associated transcription factor; Class E basic helix-loop-helix protein 32; MITF
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MITF  
• Gene symbol
  MITF
• Short name
  Anti-MITF
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  MITF Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  microphthalmia-associated transcription factor, bHLHe32 and CMM8 and MI and WS2 and WS2A, MITF and IDBG-44086 and ENSG00000187098 and 4286, protein dimerization activity, nuclei, Mitf and IDBG-172461 and ENSMUSG00000035158 and 17342, BT.29882 and IDBG-644985 and ENSBTAG00000006679 and 407219

Gene info

• Identity
  HGNC:7105
• Gene
  MITF
• Long gene name
  melanocyte inducing transcription factor
• Synonyms gene
  • WS2A
  • WS2
• Synonyms gene name
  • Waardenburg syndrome, type 2A
  • microphthalmia-associated transcription factor
  • melanogenesis associated transcription factor
• Synonyms
  • MI
  • bHLHe32
• Synonyms name
  • homolog of mouse microphthalmia
• Locus
  3p13
• Discovery year
  1993-10-27
• Entrez gene record
  4286
• Pubmed identfication
  • 8069297
  • 7874167
  • 7951321
• RefSeq identity
  • NM_198159
• Classification
  • Basic helix-loop-helix proteins
• VEGA ID
  OTTHUMG00000149921
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_776

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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