IRAK4 Antibody

• Catalog number
  F53765-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  IRAK4
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
• Notes
  Titration of the IRAK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This IRAK4 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9NWZ3
• Purity
  Antigen affinity
• Description
  Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine-like kinase (TLK) group consists of 40 tyrosine and serine-threonine kinases such as MLK (mixed-lineage kinase), LISK (LIMK/TESK), IRAK (interleukin-1 receptor-associated kinase), Raf, RIPK (receptor-interacting protein kinase), and STRK (activin and TGF-beta receptors) families.
• Immunogen
  A portion of amino acids 5-36 from the human protein was used as the immunogen for this IRAK4 antibody.
• Storage
  Aliquot the IRAK4 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  IRAK4  
• Gene symbol
  IRAK4
• Short name
  Anti-IRAK4
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to IRAK4
• Alternative technique
  antibodies
• Alternative to gene target
  interleukin-1 receptor-associated kinase 4, IRAK4 and IDBG-28022 and ENSG00000198001 and 51135, transferase activity, Extracellular, Irak4 and IDBG-177236 and ENSMUSG00000059883 and 266632, IRAK4 and IDBG-633310 and ENSBTAG00000021105 and 533692

Gene info

• Identity
  HGNC:17967
• Gene
  IRAK4
• Long gene name
  interleukin 1 receptor associated kinase 4
• Synonyms
  • NY-REN-64
• GenBank acession
  • AF155118
• Locus
  12q12
• Discovery year
  2002-09-27
• Entrez gene record
  51135
• Pubmed identfication
  • 3772297
  • 10508479
• VEGA ID
  OTTHUMG00000169425
• Locus Specific Databases
  • IRAK4base: Mutation registry for IRAK4 deficiency
  • LRG_75

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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