GPC3 Antibody

• Catalog number
  F44195-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  GPC3
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the GPC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This GPC3 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P51654
• Purity
  Antigen affinity
• Description
  Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.
• Immunogen
  A portion of amino acids 465-494 from the human protein was used as the immunogen for this GPC3 antibody.
• Storage
  Aliquot the GPC3 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  GPC3  
• Gene symbol
  GPC3-AS1, GPC3
• Short name
  Anti-GPC3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to GPC3
• Alternative technique
  antibodies
• Alternative to gene target
  glypican 3, DGSX and GTR2-2 and MXR7 and OCI-5 and SDYS and SGB and SGBS and SGBS1, GPC3 and IDBG-86754 and ENSG00000147257 and 2719, peptidyl-dipeptidase inhibitor activity, Extracellular, Gpc3 and IDBG-145213 and ENSMUSG00000055653 and 14734, GPC3 and IDBG-630953 and ENSBTAG00000020406 and 615239

Gene info

• Identity
  HGNC:52897
• Gene
  GPC3-AS1
• Long gene name
  GPC3 antisense RNA 1
• GenBank acession
  • AF085935
• Locus
  Xq26.2
• Discovery year
  2017-08-04
• Entrez gene record
  110806308
• Pubmed identfication
  • 27573079
  • 31168873
• RefSeq identity
  • NR_148713
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:4451
• Gene
  GPC3
• Long gene name
  glypican 3
• Synonyms gene
  • SDYS
• Synonyms
  • OCI-5
  • SGBS
  • SGBS1
  • SGB
  • DGSX
• Synonyms name
  • glypican proteoglycan 3
• GenBank acession
  • L47125
• Locus
  Xq26.2
• Discovery year
  1996-08-08
• Entrez gene record
  2719
• Pubmed identfication
  • 8589713
  • 9787072
• RefSeq identity
  • NM_004484
• Classification
  • Glypicans
• VEGA ID
  OTTHUMG00000022448
• Locus Specific Databases
  • LRG_505

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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