FCGRT Antibody

• Catalog number
  R32263
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  FCGRT
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P, ELISA
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml,IHC (Paraffin): 0.5-1ug/ml,ELISA: suitable
• Notes
  Optimal dilution of the FCGRT antibody should be determined by the researcher.
• Intented use
  This FCGRT antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q61559
• Purity
  Antigen affinity
• Description
  IgG receptor FcRn large subunit p51 is a protein that in humans is encoded by the FCGRT gene. This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. In addition, it is postulated that long-range cis inactivation of the FCGRT gene is responsible for hypercatabolism of IgG in myotonic dystrophy. The FCGRT gene is closely situated to the DMPK gene, which is mutant in DM.
• Immunogen
  Amino acids 54-291 of mouse FCGRT were used as the immunogen for the FCGRT antibody.
• Storage
  After reconstitution, the FCGRT antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Cytoplasmic
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  FCGRT  
• Gene symbol
  FCGRT
• Short name
  Anti-FCGRT
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to FCGRT
• Alternative technique
  antibodies
• Alternative to gene target
  Fc fragment of IgG, receptor, transporter, alpha, alpha-chain and FCRN, FCGRT and IDBG-63001 and ENSG00000104870 and 2217, beta-2-microglobulin binding, Plasma membranes, Fcgrt and IDBG-181534 and ENSMUSG00000003420 and 14132, FCGRT and IDBG-640575 and ENSBTAG00000013926 and 338062

Gene info

• Identity
  HGNC:3621
• Gene
  FCGRT
• Long gene name
  Fc fragment of IgG receptor and transporter
• Synonyms gene name
  • Fc fragment of IgG, receptor, transporter, alpha
• Synonyms
  • FCRN
  • alpha-chain
• Synonyms name
  • heavy chain of the major histocompatibility complex class I-like Fc receptor
  • transmembrane alpha chain of the neonatal receptor
  • neonatal Fc receptor
• GenBank acession
  • U12255
• Locus
  19q13.33
• Discovery year
  1995-08-23
• Entrez gene record
  2217
• Pubmed identfication
  • 7964511
  • 8646894
• Classification
  • C1-set domain containing
• VEGA ID
  OTTHUMG00000183155

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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