Cdk7 Antibody

• Catalog number
  R31240
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Cdk7
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Rat, Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the Cdk7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Cdk7 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P50613
• Purity
  Antigen affinity
• Description
  Cyclin-dependent kinase 7, also known as Cell division protein kinase 7, is an enzyme that in humans is encoded by the CDK7 gene. The protein encoded by this gene is a member of the cyclin-dependent protein kinase(CDK) family. The gene was assigned to human chromosome 5q13.2. Serine/threonine kinase involved in cell cycle control and in RNA polymerase II-mediated RNA transcription. CDK7 is the catalytic subunit of the CDK-activating kinase (CAK) complex. It is required for DNA-bound peptides-mediated transcription and cellular growth inhibition.
• Immunogen
  An amino acid sequence from the C-terminus of human Cyclin-dependent kinase 7 (RKRTEALEQGGLPKKLIF) was used as the immunogen for this Cdk7 antibody.
• Storage
  After reconstitution, the Cdk7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Cdk7  
• Gene symbol
  CDK7
• Short name
  Anti-Cdk7
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Cdk7
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1778
• Gene
  CDK7
• Long gene name
  cyclin dependent kinase 7
• Synonyms gene name
  • cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase)
  • cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)
• Synonyms
  • CAK1
  • CDKN7
  • MO15
  • STK1
  • CAK
• Locus
  5q13.2
• Discovery year
  1994-12-16
• Entrez gene record
  1022
• Pubmed identfication
  • 8069918
• RefSeq identity
  • NM_001799
• Classification
  • Cyclin dependent kinases
  • CDK activating kinase complex
• VEGA ID
  OTTHUMG00000099358

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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