Cdk7 Antibody

• Catalog number
  PB9536
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  Cdk7
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human, mouse, rat
• Analyses
  WB
• Immunogen
  E.coli-derived human Cdk7 recombinant protein (Position: D31-F346). Human Cdk7 shares 94.9% and 96.1% amino acid (aa) sequence identity with mouse and rat Cdk7, respectively.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the Cdk7 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The Cdk7 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  Cyclin-dependent kinase 7, also known as cell division protein kinase 7, is an enzyme that in humans is encoded by the CDK7 gene. The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. The gene was assigned to human chromosome 5q13.2. Serine/threonine kinase involved in cell cycle control and in RNA polymerase II-mediated RNA transcription. CDK7 is the catalytic subunit of the CDK-activating kinase (CAK) complex. It is required for DNA-bound peptides-mediated transcription and cellular growth inhibition.
• Related articles
  1. Chen, J., Larochelle, S., Li, X., Suter, B. Xpd/Ercc2 regulates CAK activity and mitotic progression. Nature 424: 228-232, 2003. 2. Larochelle, S., Merrick, K. A., Terret, M.-E., Wohlbold, L., Barboza, N. M., Zhang, C., Shokat, K. M., Jallepalli, P. V., Fisher, R. P. Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells. Molec. Cell 25: 839-850, 2007. 3. Levedakou, E. N., He, M., Baptist, E. W., Craven, R. J., Cance, W. G., Welcsh, P. L., Simmons, A., Naylor, S. L., Leach, R. L., Lewis, T. B., Bowcock, A., Liu, E. T. Two novel human serine/threonine kinases with homologies to the cell cycle regulating Xenopus MO15, and NIMA kinases: cloning and characterization of their expression pattern. Oncogene 9: 1977-1988, 1994. 4. Shiekhattar, R., Mermelstein, F., Fisher, R. P., Drapkin, R., Dynlacht, B., Wessling, H. C., Morgan, D. O., Reinberg. Cdk-activating kinase complex is a component of human transcription factor TFIIH. Nature 374: 283-287, 1995.
• Gene Name
  CDK7
• Protein Name
  Cyclin-dependent kinase 7
• Gene Full Name
  cyclin-dependent kinase 7
• Synonyms
  39 kDa protein kinase antibody|CAK antibody|CAK1 antibody|Cdk activating kinase antibody| CDK-activating kinase 1 antibody|CDK-activating kinase antibody|cdk7 antibody|CDK7_HUMAN antibody|CDKN7 antibody|Cell division protein kinase 7 antibody|Cyclin dependent kinase 7 antibody|cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) antibody|Cyclin-dependent kinase 7 antibody|HCAK antibody|Homolog of Xenopus MO15 Cdk activating kinase antibody|Kinase subunit of CAK antibody|MO15 antibody|MO15, Xenopus, homolog of antibody|P39 Mo15 antibody|p39MO15 antibody|Serine threonine kinase Stk1 antibody|Serine/threonine protein kinase 1 antibody|Serine/threonine protein kinase MO15 antibody|STK1 antibody|TFIIH basal transcription factor complex kinase subunit antibody
• Uniprot ID
  P50613
• Entrez GeneID
  1022
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Cdk7  
• Gene symbol
  CDK7
• Short name
  Cdk7 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Cdk7 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1778
• Gene
  CDK7
• Long gene name
  cyclin dependent kinase 7
• Synonyms gene name
  • cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase)
  • cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)
• Synonyms
  • CAK1
  • CDKN7
  • MO15
  • STK1
  • CAK
• Locus
  5q13.2
• Discovery year
  1994-12-16
• Entrez gene record
  1022
• Pubmed identfication
  • 8069918
• RefSeq identity
  • NM_001799
• Classification
  • Cyclin dependent kinases
  • CDK activating kinase complex
• VEGA ID
  OTTHUMG00000099358

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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