Cdk2 Antibody

• Catalog number
  R30623
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Cdk2
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the Cdk2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Cdk2 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P24941
• Purity
  Antigen affinity
• Description
  Cyclin-Dependent Kinase 2 is also know as p33. The protein is highly homologous to p34 (CDC2) kinase and more significantly homologous to Xenopus Eg1 kinase, suggesting thatCdk2is the human homolog of Eg1. The gene is mapped to 12q13, the same region to which theCdk4gene maps. Human Cyclin A binds independently to two kinases, p34/Cdc2) or p33/Cdk2. In adenovirus-transformed cells, the viral E1A oncoprotein seems to associate with p33/Cyclin A but not with p34(cdc2)/cyclin A. The gene for p33 shares 65% sequence identity with p34(cdc2). Cdk2 plays a unique role in cell cycle regulation of vertebrate cells.
• Immunogen
  Amino acids 277-298 (AKAALAHPFFQDVTKPVPHLRL) were used as the immunogen for this Cdk2 antibody (100% homologous in human, mouse and rat).
• Storage
  After reconstitution, the Cdk2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Cdk2  
• Gene symbol
  CDK2, CACUL1, CDK2AP1
• Short name
  Anti-Cdk2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Cdk2
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1771
• Gene
  CDK2
• Long gene name
  cyclin dependent kinase 2
• GenBank acession
  • M68520
• Locus
  12q13.2
• Discovery year
  1992-02-28
• Entrez gene record
  1017
• Pubmed identfication
  • 1717994
  • 8275715
• Classification
  • Cyclin dependent kinases
• VEGA ID
  OTTHUMG00000170575

Gene info

• Identity
  HGNC:23727
• Gene
  CACUL1
• Long gene name
  CDK2 associated cullin domain 1
• Synonyms gene
  • C10orf46
• Synonyms gene name
  • chromosome 10 open reading frame 46
  • CDK2-associated, cullin domain 1
• Synonyms
  • FLJ40409
  • MGC33215
  • CAC1
• Synonyms name
  • Cdk-Associated Cullin1
• GenBank acession
  • AK097728
• Locus
  10q26.11
• Discovery year
  2003-12-07
• Entrez gene record
  143384
• Pubmed identfication
  • 19829063
• RefSeq identity
  • NM_153810
• VEGA ID
  OTTHUMG00000019138

Gene info

• Identity
  HGNC:14002
• Gene
  CDK2AP1
• Long gene name
  cyclin dependent kinase 2 associated protein 1
• Synonyms gene name
  • CDK2-associated protein 1
• Synonyms
  • DORC1
  • doc-1
  • DOC1
  • ST19
  • p12DOC-1
• GenBank acession
  • AB006077
• Locus
  12q24.31
• Discovery year
  2001-06-21
• Entrez gene record
  8099
• Pubmed identfication
  • 9331572
  • 9506968
• RefSeq identity
  • NM_004642
• VEGA ID
  OTTHUMG00000168854

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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