Cdk2 Antibody

• Catalog number
  PA1547
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  Cdk2
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human, rat Predicted to work with: mouse
• Analyses
  WB
• Immunogen
  A synthetic peptide corresponding to a sequence at the C-terminus of human Cdk2(277-298aa AKAALAHPFFQDVTKPVPHLRL), identical to the related rat and mouse sequences.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the Cdk2 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The Cdk2 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  CDK2, Cyclin-Dependent Kinase2, is also know as P33. The CDK2 protein was highly homologous to p34(CDC2) kinase and more significantly homologous to Xenopus Eg1 kinase, suggesting that CDK2 is the human homolog of Eg1. The CDK2 gene is mapped to 12q13, the same region to which the CDK4 gene maps. Human cyclin A binds independently to 2 kinases, p34(cdc2) or p33. In adenovirus-transformed cells, the viral E1A oncoprotein seems to associate with p33/cyclin A but not with p34(cdc2)/cyclin A. The gene for p33 shares 65% sequence identity with p34(cdc2). P33(cdk2) plays a unique role in cell cycle regulation of vertebrate cells.
• Related articles
  1. Demetrick, D. J., Zhang, H., Beach, D. H.Chromosomal mapping of human CDK2, CDK4, and CDK5 cell cycle kinase genes.Cytogenet. Cell Genet. 66: 72-74, 1994. 2. Tsai, L.-H., Harlow, E., Meyerson, M.Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated P33 kinase.Nature 353: 174-177, 1991.
• Gene Name
  CDK2
• Protein Name
  Cyclin-dependent kinase 2
• Gene Full Name
  cyclin-dependent kinase 2
• Synonyms
  Cdc2 related protein kinase antibody|cdc2-related protein kinase antibody|Cdk 2 antibody|CDK2 antibody|CDK2_HUMAN antibody|Cell devision kinase 2 antibody|Cell division kinase 2 antibody|Cell division protein kinase 2 antibody|Cyclin dependent kinase 2 antibody|cyclin dependent kinase 2-alpha antibody|Cyclin-dependent kinase 2 antibody|p33 protein kinase antibody|p33(CDK2) antibody
• Uniprot ID
  P24941
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Cdk2  
• Gene symbol
  CDK2, CACUL1, CDK2AP1
• Short name
  Cdk2 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Cdk2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1771
• Gene
  CDK2
• Long gene name
  cyclin dependent kinase 2
• GenBank acession
  • M68520
• Locus
  12q13.2
• Discovery year
  1992-02-28
• Entrez gene record
  1017
• Pubmed identfication
  • 1717994
  • 8275715
• Classification
  • Cyclin dependent kinases
• VEGA ID
  OTTHUMG00000170575

Gene info

• Identity
  HGNC:23727
• Gene
  CACUL1
• Long gene name
  CDK2 associated cullin domain 1
• Synonyms gene
  • C10orf46
• Synonyms gene name
  • chromosome 10 open reading frame 46
  • CDK2-associated, cullin domain 1
• Synonyms
  • FLJ40409
  • MGC33215
  • CAC1
• Synonyms name
  • Cdk-Associated Cullin1
• GenBank acession
  • AK097728
• Locus
  10q26.11
• Discovery year
  2003-12-07
• Entrez gene record
  143384
• Pubmed identfication
  • 19829063
• RefSeq identity
  • NM_153810
• VEGA ID
  OTTHUMG00000019138

Gene info

• Identity
  HGNC:14002
• Gene
  CDK2AP1
• Long gene name
  cyclin dependent kinase 2 associated protein 1
• Synonyms gene name
  • CDK2-associated protein 1
• Synonyms
  • DORC1
  • doc-1
  • DOC1
  • ST19
  • p12DOC-1
• GenBank acession
  • AB006077
• Locus
  12q24.31
• Discovery year
  2001-06-21
• Entrez gene record
  8099
• Pubmed identfication
  • 9331572
  • 9506968
• RefSeq identity
  • NM_004642
• VEGA ID
  OTTHUMG00000168854

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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