CCR8 Antibody

• Catalog number
  F40687-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  CCR8
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, FACS, ELISA
• Recommended dilutions
  Western blot: 1:1000,Flow Cytometry: 1:10-1:50
• Notes
  Titration of the CCR8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This CCR8 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P51685
• Purity
  Antigen affinity
• Description
  CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. CCR8 is located at the chemokine receptor gene cluster region.
• Immunogen
  A portion of amino acids 290-317 from the human protein was used as the immunogen for this CCR8 antibody.
• Storage
  Aliquot the CCR8 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CCR8  
• Gene symbol
  CCR8
• Short name
  Anti-CCR8
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to CCR8
• Alternative technique
  antibodies
• Alternative to gene target
  chemokine (C-C motif) receptor 8, CC-CKR-8 and CCR-8 and CDw198 and CKRL1 and CMKBR8 and CMKBRL2 and CY6 and GPRCY6 and TER1, CCR8 and IDBG-26700 and ENSG00000179934 and 1237, C-C chemokine receptor activity, Plasma membranes, Ccr8 and IDBG-205018 and ENSMUSG00000042262 and 12776, BT.30825 and IDBG-647797 and ENSBTAG00000015483 and 407772

Gene info

• Identity
  HGNC:1609
• Gene
  CCR8
• Long gene name
  C-C motif chemokine receptor 8
• Synonyms gene
  • CMKBRL2
  • CMKBR8
• Synonyms gene name
  • chemokine (C-C motif) receptor 8
• Synonyms
  • CY6
  • TER1
  • CKR-L1
  • GPR-CY6
  • CDw198
• GenBank acession
  • D49919
• Locus
  3p22.1
• Discovery year
  1997-04-21
• Entrez gene record
  1237
• Pubmed identfication
  • 8816377
  • 8886020
• RefSeq identity
  • NM_005201
• Classification
  • C-C motif chemokine receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000131290

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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