ANGPTL3 Antibody

• Catalog number
  F49810-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  ANGPTL3
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the ANGPTL3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This ANGPTL3 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9Y5C1
• Purity
  Purified
• Description
  ANGPTL3 is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.
• Immunogen
  A portion of amino acids 82-114 from the human protein was used as the immunogen for this ANGPTL3 antibody.
• Storage
  Aliquot the ANGPTL3 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ANGPTL3  
• Gene symbol
  ANGPTL3
• Short name
  Anti-ANGPTL3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to ANGPTL3
• Alternative technique
  antibodies
• Alternative to gene target
  angiopoietin-like 3, ANGPTL3 and IDBG-99367 and ENSG00000132855 and 27329, growth factor activity, Extracellular, Angptl3 and IDBG-166252 and ENSMUSG00000028553 and 30924, ANGPTL3 and IDBG-638594 and ENSBTAG00000021386 and 782603

Gene info

• Identity
  HGNC:491
• Gene
  ANGPTL3
• Long gene name
  angiopoietin like 3
• Synonyms gene
  • ANGPT5
• Synonyms gene name
  • angiopoietin-like 3
• Synonyms name
  • angiopoietin 5
• GenBank acession
  • AF152562
• Locus
  1p31.3
• Discovery year
  2000-02-07
• Entrez gene record
  27329
• Pubmed identfication
  • 10644446
• RefSeq identity
  • NM_014495
• Classification
  • Fibrinogen C domain containing
  • Receptor ligands
  • Angiopoietin like family
• VEGA ID
  OTTHUMG00000009146

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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