Angiotensin Converting Enzyme Antibody (ACE)
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Catalog number
R31319
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Price
Please ask
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Size
0.1mg
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Category
Antibody
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Concentration
0.5mg/ml if reconstituted with 0.2ml sterile DI water
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Form
Antigen affinity purified
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Conjugation
Unconjugated
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Clone
Polyclonal antibody
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Recognised antigen
Angiotensin Converting Enzyme (ACE)
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Host animal
Rabbit (Oryctolagus cuniculus)
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Clonality
Polyclonal (rabbit origin)
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Species reactivity
Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applications
WB
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Recommended dilutions
Western blot: 0.5-1ug/ml
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Notes
The stated application concentrations are suggested starting amounts. Titration of the Angiotensin Converting Enzyme antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented use
This Angiotensin Converting Enzyme antibodyis to be used only for research purposes and not for diagnostics..
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Uniprot
P12821
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Purity
Antigen affinity
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Description
Angiotensin converting enzyme (ACE), also called DCP or CD143 is a zinc-containing dipeptidyl carboxypeptidase widely distributed in mammalian tissues and is though to play a critical role in blood pressure regulation. This gene is mapped to 17q23.3. This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II.
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Immunogen
An amino acid sequence from the N-terminus of human ACE (ANLPLAKRQQYNALL) was used as the immunogen for this Angiotensin Converting Enzyme antibody.
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Storage
After reconstitution, the Angiotensin Converting Enzyme antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
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Properties
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Additional description
Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
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French translation
anticorps
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Gene target
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Gene symbol
ACE
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Short name
Anti-Angiotensin Converting Enzyme (ACE)
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Technique
Antibody, Enzyme, antibodies against human proteins, antibodies for, enzymes
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Isotype
Rabbit IgG
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Alternative name
Antibodies to Angiotensin Converting Enzyme (ACE)
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Alternative technique
antibodies, enzymes
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Alternative to gene target
Angiotensin-converting enzyme; Uncharacterized protein, ACE and IDBG-728302 and ENSG00000264813 and, peptidyl-dipeptidase activity, Plasma membranes
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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