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Angiotensin Converting Enzyme Antibody (ACE)

  • Catalog number
    F50773-0.08ML
  • Product name
    Angiotensin Converting Enzyme Antibody (ACE)
  • Size
    0.08 ml
  • Short name
    Anti-Angiotensin Converting Enzyme (ACE)
  • Category
    Antibody
  • Concentration
    In 1X PBS, pH 7.4, with 0.09% sodium azide
  • Form
    Purified
  • Conjugation
    Unconjugated
  • Clone
    Polyclonal antibody
  • Recognised antigen
    Angiotensin Converting Enzyme (ACE)
  • Host animal
    Rabbit (Oryctolagus cuniculus)
  • Clonality
    Polyclonal (rabbit origin)
  • Isotype
    Rabbit Ig
  • Species reactivity
    Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
  • Tested applications
    WB, ELISA
  • Recommended dilutions
    Western blot: 1:1000
  • Notes
    Titration of the ACE antibody may be required due to differences in protocols and secondary/substrate sensitivity.
  • Intented use
    This ACE antibodyis to be used only for research purposes and not for diagnostics..
  • Uniprot
    P12821
  • Purity
    Purified
  • Description
    ACE is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active.
  • Immunogen
    A portion of amino acids 1274-1306 from the human protein was used as the immunogen for this ACE antibody.
  • Storage
    Aliquot the ACE antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
  • Alternative to gene target
    • [ "Angiotensin-converting enzyme; Uncharacterized protein", "ACE and IDBG-728302 and ENSG00000264813 and", "peptidyl-dipeptidase activity", "Plasma membranes" ]
  • Gene target
    Angiotensin Converting ACE
    • Gene info
  • Gene symbol
    ACE
  • isotype filter
    • Rabbit Ig
  • technique filter
    • Antibody
    • Enzyme
  • Technique
    Antibody, Enzyme, antibodies against human proteins, antibodies for, enzymes
  • Alternative technique
    antibodies, enzymes