ABCB11 Antibody

• Catalog number
  R31844
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  ABCB11
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  Optimal dilution of the ABCB11 antibody should be determined by the researcher.
• Intented use
  This ABCB11 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O95342
• Purity
  Antigen affinity
• Description
  Bile Salt Export Pump (BSEP) is a protein which in humans is encoded by the ABCB 11 gene. It is a member of the superfamily of ATP-binding cassette (ABC) transporters, also known as ABCB11. It is mapped to chromosome 2q24. The BSEP protein is mainly expressed in the liver. ABCB11 is a gene associated with progressive familial intrahepatic cholestasis type 2 (PFIC2) which caused by mutations in the ABCB11 gene will increases the risk of hepatocellular carcinoma in early life.
• Immunogen
  Amino acids KYGDNTKEIPMERVIAAAKQAQLHD of human ABCB11 were used as the immunogen for the ABCB11 antibody.
• Storage
  After reconstitution, the ABCB11 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Membrane
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ABCB11  
• Gene symbol
  ABCB11
• Short name
  Anti-ABCB11
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to ABCB11
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:42
• Gene
  ABCB11
• Long gene name
  ATP binding cassette subfamily B member 11
• Synonyms gene
  • BSEP
  • PFIC2
• Synonyms gene name
  • progressive familial intrahepatic cholestasis 2
  • bile salt export pump
  • ATP-binding cassette, sub-family B (MDR/TAP), member 11
• Synonyms
  • ABC16
  • SPGP
  • PFIC-2
  • PGY4
• Synonyms name
  • ABC member 16, MDR/TAP subfamily
• GenBank acession
  • AF091582
• Locus
  2q31.1
• Discovery year
  1998-09-25
• Entrez gene record
  8647
• Pubmed identfication
  • 9806540
• RefSeq identity
  • NM_003742
• Classification
  • ATP binding cassette subfamily B
• VEGA ID
  OTTHUMG00000154039
• Locus Specific Databases
  • CCHMC-BMI & UC Hearing Loss Mutation Database
  • LRG_1199

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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