UBASH3B (Ubiquitin-associated and SH3 Domain-containing B, Cbl-interacting Protein 4, CLIP4, Suppressor of T Cell Receptor Signaling 2, STS 2, STS2, STS-2, T Cell Ubiquitin Ligand, TULA)[UBASH3B]

  • Catalog number
    MBS641201
  • Price
    Please ask
  • Size
    NA
  • Products_type
    Antibody
  • Reactivity
    Human, Rat
  • Description
    For cells, cell lines and tissues in culture till half confluency. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels. Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created. Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.
  • Gene target
    UBASH3B   Ubiquitin-associated   SH3   Domain   Cbl-interacting   Protein   CLIP4   Suppressor   Receptor   Signaling   STS   STS2   STS-2   Ubiquitin   Ligand   TULA   [UBASH3B]  
  • Gene symbol
    UBASH3B, UBASH3A, STS, STSP1, CLIP4, MIR7-2, MIR329-2, MIR512-2, MIR521-2, MIR1289-2
  • Short name
    UBASH3B (Ubiquitin-associated SH3 Domain- B, Cbl-interacting Protein 4, CLIP4, Suppressor of T Receptor Signaling 2, STS 2, STS2, STS-2, T Ubiquitin Ligand, TULA)[UBASH3B]
  • Host
    Sheep
  • Alternative name
    UBASH3B (Ubiquitin-associated and SH3 Domain-containing B, Cbl proto-oncogene, E3 ubiquitin protein ligase-interacting Protein 4, CLIP4, Suppressor on T cellular Receptor Signaling 2, STS 2, STS2, STS-2, T cellular Ubiquitin Ligand, TULA)[UBASH3B]
  • Alternative to gene target
    Cbl proto-oncogene, E3 ubiquitin protein ligase, C-CBL and CBL2 and FRA11B and NSLL and RNF55, CBL and IDBG-74417 and ENSG00000110395 and 867, ephrin receptor binding, nuclei, Cbl and IDBG-155970 and ENSMUSG00000034342 and 12402, CBL and IDBG-631730 and ENSBTAG00000006817 and 527418
  • Tissue
    cell
Gene info
Gene info
Gene info
Gene info
Gene info
  • Identity
    HGNC:26108
  • Gene
    CLIP4
  • Long gene name
    CAP-Gly domain containing linker protein family member 4
  • Synonyms gene
  • Synonyms gene name
    • restin-like 2
    • CAP-GLY domain containing linker protein family, member 4
  • Synonyms
  • GenBank acession
  • Locus
    2p23.2
  • Discovery year
    2004-11-29
  • Entrez gene record
    79745
  • RefSeq identity
  • Classification
    • Ankyrin repeat domain containing
  • VEGA ID
    OTTHUMG00000097837
Gene info
Gene info
Gene info
Gene info
Gene info
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Filters
UBASH3B Ubiquitin associated SH3 Domain B Cbl interacting Pr
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