UBASH3A, ID (UBASH3A, STS2, Ubiquitin-associated and SH3 domain-containing protein A, Cbl-interacting protein 4, Suppressor of T-cell receptor signaling 2, T-cell ubiquitin ligand 1)[UBASH3A]
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Catalog numberMBS641469
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PricePlease ask
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SizeNA
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Products_typeAntibody
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ReactivityMouse
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DescriptionFor cells, cell lines and tissues in culture till half confluency. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels. Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created. Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.
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Gene target
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Gene symbolUBASH3A
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Short nameUBASH3A, ID (UBASH3A, STS2, Ubiquitin-associated SH3 domain- protein A, Cbl-interacting protein 4, Suppressor of T- receptor signaling 2, T- ubiquitin ligand 1)[UBASH3A]
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HostRabbit
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Alternative nameubiquitin associated and SH3 domain containing A, ID (ubiquitin associated and SH3 domain containing A, STS2, Ubiquitin-associated and SH3 domain-containing protein A, Cbl proto-oncogene, E3 ubiquitin protein ligase-interacting protein 4, Suppressor on T-cellular receptor signaling 2, T-cellular ubiquitin ligand 1)[ubiquitin associated and SH3 domain containing A]
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Alternative to gene targetubiquitin associated and SH3 domain containing A, UBASH3A and IDBG-4392 and ENSG00000160185 and 53347, protein binding, nuclei, Ubash3a and IDBG-163965 and ENSMUSG00000042345 and 328795, UBASH3A and IDBG-639437 and ENSBTAG00000023398 and 514555
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Tissuecell
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Gene info
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Identity
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Gene
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Long gene nameubiquitin associated and SH3 domain containing A
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-05-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
