Tumor Necrosis Factor alpha (TNF-a)
-
Catalog number
MBS590025
-
Price
Please ask
-
Size
3x192 Wells
-
-
Products_type
ELISA Kit
-
Products_short_name
[Tumor Necrosis Factor alpha]
-
Products_name_syn
[Tumor Necrosis Factor alpha (TNF-alpha); Tumor Necrosis Factor alpha (TNF-a)]
-
Other_names
[TNF-alpha; Tumor necrosis factor; tumor necrosis factor; APC1 protein; TNF, macrophage-derived; TNF, monocyte-derived; TNF-a; cachectin; tumor necrosis factor ligand superfamily member 2; tumor necrosis factor-alpha; tumor necrosis factor; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a]
-
Products_gene_name
[TNF-a]
-
Other_gene_names
[TNF; TNF; DIF; TNFA; TNFSF2; TNF-alpha]
-
Specificity
This sandwich ELISA recognises both natural and recombinant human TNF-?. This kit exhibits no significant cross-reactivity with human TGF, MCP-1, MCP-3, M-CSF, GM-CSF, EGF, IL-1?, IL-8, and IL-16.
-
Description
The Tumor Necrosis Factor alpha (TNF-a) is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
-
Gene
Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
-
Gene target
-
Gene symbol
TNF, TNFRSF1A, TNFRSF1B, LTBR
-
Short name
Tumor Necrosis Factor alpha (TNF-a)
-
Alternative name
Tumor Necrosis Factor a (tumor necrosis factor-a)
-
Alternative to gene target
tumor necrosis factor, DIF and TNF-alpha and TNFA and TNFSF2, TNF and IDBG-300259 and ENSG00000232810 and 7124, transcription regulatory region DNA binding, Extracellular, Tnf and IDBG-177358 and ENSMUSG00000024401 and 21926, TNF and IDBG-634161 and ENSBTAG00000025471 and 280943
-
Tissue
tumor
-
Gene info
-
Identity
-
Gene
-
Long gene name
tumor necrosis factor
-
Synonyms gene
-
Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
1986-01-01
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Tumor necrosis factor superfamily
-
VEGA ID
Gene info
Gene info
Gene info
MeSH Data
-
Name
-
Concept
Scope note:
A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
-
Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products