Transcription Factor 7-like 1 (TCF7L1, HMG Box Transcription Factor 3, T Cell Factor 3, TCF3, TCF-3)

  • Catalog number
    MBS629714
  • Price
    Please ask
  • Size
    0.1 mg
  • Products_type
    Antibody
  • Products_short_name
    [Transcription Factor 7-like 1]
  • Products_name_syn
    [Anti -Transcription Factor 7-like 1 (TCF7L1, HMG Box Transcription Factor 3, T Cell Factor 3, TCF3, TCF-3)]
  • Other_names
    [transcription factor 7-like 1; Transcription factor 7-like 1; transcription factor 7-like 1; OTTHUMP00000160497; HMG box transcription factor 3; transcription factor 7-like 1 (T-cell specific, HMG-box); HMG box transcription factor 3]
  • Other_gene_names
    [TCF7L1; TCF7L1; TCF3; TCF-3; TCF3]
  • Clonality
    Polyclonal
  • Reactivity
    Human
  • Specificity
    Recognizes human TCF7L1.
  • Purity
    Affinity Purified Purified by immunoaffinity chromatography.
  • Form
    Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with PBS, 0.02% sodium azide.
  • Storage_stability
    Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS, 0.02% NaN3. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
  • Tested_application
    Western Blot (WB)
  • Description
    For cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
  • Gene target
    Transcription   Factor   7-like   TCF7L1   HMG   Box   Transcription   Factor   Factor   TCF3   TCF-3  
  • Gene symbol
    TCF7L1, TCF3, TCF7L1-IT1, TCF7, TCF7L2, HGF, MIR1302-3, MIR509-3, MIR7-3
  • Short name
    Transcription Factor 7-like 1 (TCF7L1, HMG Box Transcription Factor 3, T Factor 3, TCF3, TCF-3)
  • Host
    Sheep
  • Isotype
    IgG
  • Alternative name
    Transcription Factor 7-like 1 (transcription factor 7-like 1 (T-cellular specific, HMG-box), HMG Box Transcription Factor 3, T cellular Factor 3, transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47), TCF-3)
  • Alternative to gene target
    transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47), bHLHb21 and E2A and E47 and ITF1 and TCF-3 and VDIR, TCF3 and IDBG-14881 and ENSG00000071564 and 6929, E-box binding, nuclei, Tcf3 and IDBG-174161 and ENSMUSG00000020167 and 21423, TCF3 and IDBG-645672 and ENSBTAG00000008695 and 530616
  • Tissue
    cell
Gene info
  • Identity
    HGNC:11640
  • Gene
    TCF7L1
  • Long gene name
    transcription factor 7 like 1
  • Synonyms gene
  • Synonyms gene name
    • transcription factor 7-like 1 (T-cell specific, HMG-box)
  • GenBank acession
  • Locus
    2p11.2
  • Discovery year
    1998-01-20
  • Entrez gene record
    83439
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • TCF/LEF transcription factor family
    • Wnt enhanceosome complex
  • VEGA ID
    OTTHUMG00000130026
Gene info
Gene info
  • Identity
    HGNC:41388
  • Gene
    TCF7L1-IT1
  • Long gene name
    TCF7L1 intronic transcript 1
  • Synonyms gene name
    • TCF7L1 intronic transcript 1 (non-protein coding)
  • Locus
    2p11.2
  • Discovery year
    2011-05-19
  • Classification
    • Intronic transcripts
  • VEGA ID
    OTTHUMG00000153211
Gene info
  • Identity
    HGNC:11639
  • Gene
    TCF7
  • Long gene name
    transcription factor 7
  • Synonyms gene name
    • transcription factor 7 (T-cell specific, HMG-box)
  • Synonyms
  • Synonyms name
  • GenBank acession
  • Locus
    5q31.1
  • Discovery year
    1991-08-18
  • Entrez gene record
    6932
  • RefSeq identity
  • Classification
    • TCF/LEF transcription factor family
    • Wnt enhanceosome complex
  • VEGA ID
    OTTHUMG00000129124
Gene info
  • Identity
    HGNC:11641
  • Gene
    TCF7L2
  • Long gene name
    transcription factor 7 like 2
  • Synonyms gene
  • Synonyms gene name
    • transcription factor 7-like 2 (T-cell specific, HMG-box)
  • Synonyms
  • GenBank acession
  • Locus
    10q25.2-q25.3
  • Discovery year
    1998-01-20
  • Entrez gene record
    6934
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • TCF/LEF transcription factor family
    • Wnt enhanceosome complex
  • VEGA ID
    OTTHUMG00000019070
Gene info
Gene info
Gene info
Gene info
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Filters
Transcription Factor 7 like 1 TCF7L1 HMG Box Transcription F
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