Transcription Factor 7-like 1 (TCF7L1, HMG Box Transcription Factor 3, T Cell Factor 3, TCF3, TCF-3)

• Catalog number
  GEN632630
• Price
  Please ask
• Size
  100ul

• Also known as
  Transcription Factor 7-like 1
• Other names
  transcription factor 7-like 1; Transcription factor 7-like 1; transcription factor 7-like 1; OTTHUMP00000160497; HMG box transcription factor 3; transcription factor 7-like 1 (T-cell specific, HMG-box); HMG box transcription factor 3
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  TCF7L1; TCF7L1; TCF3; TCF-3; TCF3
• Gene name synonims
  TCF7L1; TCF7L1; TCF3; TCF-3; TCF3
• Other gene names
  TCF7L1; TCF7L1; TCF3; TCF-3; TCF3
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG
• Clone
  9H520
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes human TCF-3.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Supernatant
• Form Appearance
  Supplied as a liquid in 50mM Tris-Glycine, pH 7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide and 0.05% BSA.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. Long-term storage should be done after aliquoting the antibody and freezing the aliqotes at -20 degrees Celsius. Under these conditions the aliquots will be stable for at least one year if kept at -20 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested applications
  Western Blot (WB), Flow Cytometry (FC/FACS)
• Description
  For cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.

• Gene target
  Transcription   Factor   7-like   TCF7L1   HMG   Box   Transcription   Factor   Factor   TCF3   TCF-3  
• Gene symbol
  TCF7L1, TCF3, TCF7L1-IT1, TCF7, TCF7L2, HGF, MIR1302-3, MIR509-3, MIR7-3
• Short name
  Transcription Factor 7-like 1 (TCF7L1, HMG Box Transcription Factor 3, T Factor 3, TCF3, TCF-3)
• Alternative name
  Anti-Transcription Factor 7-like 1 (TCF7L1, HMG Box Transcription Factor 3, T Cell Factor 3, TCF3, TCF-3)
• Alternative to gene target
  transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47), bHLHb21 and E2A and E47 and ITF1 and TCF-3 and VDIR, TCF3 and IDBG-14881 and ENSG00000071564 and 6929, E-box binding, nuclei, Tcf3 and IDBG-174161 and ENSMUSG00000020167 and 21423, TCF3 and IDBG-645672 and ENSBTAG00000008695 and 530616
• Tissue
  cell

Gene info

• Identity
  HGNC:11640
• Gene
  TCF7L1
• Long gene name
  transcription factor 7 like 1
• Synonyms gene
  • TCF3
• Synonyms gene name
  • transcription factor 7-like 1 (T-cell specific, HMG-box)
• GenBank acession
  • X62870
• Locus
  2p11.2
• Discovery year
  1998-01-20
• Entrez gene record
  83439
• Pubmed identfication
  • 1741298
  • 11085512
• RefSeq identity
  • NM_031283
• Classification
  • TCF/LEF transcription factor family
  • Wnt enhanceosome complex
• VEGA ID
  OTTHUMG00000130026

Gene info

• Identity
  HGNC:11633
• Gene
  TCF3
• Long gene name
  transcription factor 3
• Synonyms
  • E2A
  • ITF1
  • MGC129647
  • MGC129648
  • bHLHb21
  • VDIR
  • E47
  • p75
• Synonyms name
  • transcription factor E2-alpha
  • immunoglobulin transcription factor 1
  • kappa-E2-binding factor
  • E2A immunoglobulin enhancer-binding factor E12/E47
  • VDR interacting repressor
• GenBank acession
  • M65214
• Locus
  19p13.3
• Discovery year
  1990-07-26
• Entrez gene record
  6929
• Pubmed identfication
  • 2308859
  • 1967983
• RefSeq identity
  • NM_003200
• Classification
  • Basic helix-loop-helix proteins
• VEGA ID
  OTTHUMG00000180031
• Locus Specific Databases
  • LRG_1325

Gene info

• Identity
  HGNC:41388
• Gene
  TCF7L1-IT1
• Long gene name
  TCF7L1 intronic transcript 1
• Synonyms gene name
  • TCF7L1 intronic transcript 1 (non-protein coding)
• Locus
  2p11.2
• Discovery year
  2011-05-19
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000153211

Gene info

• Identity
  HGNC:11639
• Gene
  TCF7
• Long gene name
  transcription factor 7
• Synonyms gene name
  • transcription factor 7 (T-cell specific, HMG-box)
• Synonyms
  • TCF-1
• Synonyms name
  • T-cell-factor-7
• GenBank acession
  • Z47362
• Locus
  5q31.1
• Discovery year
  1991-08-18
• Entrez gene record
  6932
• RefSeq identity
  • NM_201634
• Classification
  • TCF/LEF transcription factor family
  • Wnt enhanceosome complex
• VEGA ID
  OTTHUMG00000129124

Gene info

• Identity
  HGNC:11641
• Gene
  TCF7L2
• Long gene name
  transcription factor 7 like 2
• Synonyms gene
  • TCF4
• Synonyms gene name
  • transcription factor 7-like 2 (T-cell specific, HMG-box)
• Synonyms
  • TCF-4
• GenBank acession
  • X62871
• Locus
  10q25.2-q25.3
• Discovery year
  1998-01-20
• Entrez gene record
  6934
• Pubmed identfication
  • 1741298
• RefSeq identity
  • NM_030756
• Classification
  • TCF/LEF transcription factor family
  • Wnt enhanceosome complex
• VEGA ID
  OTTHUMG00000019070

Gene info

• Identity
  HGNC:4893
• Gene
  HGF
• Long gene name
  hepatocyte growth factor
• Synonyms gene
  • DFNB39
• Synonyms gene name
  • deafness, autosomal recessive 39
  • hepatocyte growth factor (hepapoietin A; scatter factor)
• Synonyms
  • SF
  • F-TCF
  • HGFB
  • HPTA
• Synonyms name
  • hepatopoietin A
  • fibroblast-derived tumor cytotoxic factor
  • scatter factor
  • lung fibroblast-derived mitogen
• Locus
  7q21.11
• Discovery year
  1991-06-07
• Entrez gene record
  3082
• Pubmed identfication
  • 1837206
  • 19576567
• RefSeq identity
  • NM_000601
• VEGA ID
  OTTHUMG00000023804

Gene info

• Identity
  HGNC:35295
• Gene
  MIR1302-3
• Long gene name
  microRNA 1302-3
• Synonyms gene
  • MIRN1302-3
• Synonyms
  • hsa-mir-1302-3
• Locus
  2q14.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302128
• RefSeq identity
  • NR_031632
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:33675
• Gene
  MIR509-3
• Long gene name
  microRNA 509-3
• Synonyms gene
  • MIRN509-3
• Synonyms
  • hsa-mir-509-3
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126337
• RefSeq identity
  • NR_030629
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:31640
• Gene
  MIR7-3
• Long gene name
  microRNA 7-3
• Synonyms gene
  • MIRN7-3
• Synonyms
  • hsa-mir-7-3
• Locus
  19p13.3
• Discovery year
  2004-04-23
• Entrez gene record
  407045
• RefSeq identity
  • NR_029607
• Classification
  • MicroRNA MIR7 family

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