Toll-like receptor adapter molecule 1, TRIF (TICAM-1)

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Description

Whole adhesion and interacting molecules are present in lysates used as reference for ELISA quantification of these molecules and their subunits. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Gene target

Toll-like receptor adapter molecule TRIF TICAM-1
Gene symbol

TICAM1, TICAM2, TRIM69, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1, MIR101-1
Short name

Toll-like receptor adapter molecule 1, TRIF (TICAM-1)
Alternative name

Toll-like receptor adapter molecule 1, TRIF (TICAM-1)

Identity

HGNC:18348
Gene

TICAM1
Long gene name

toll like receptor adaptor molecule 1
Synonyms gene name
- toll-like receptor adaptor molecule 1
Synonyms
- TRIF
- TICAM-1
- MGC35334
- PRVTIRB
Synonyms name
- TIR domain-containing adapter molecule 1
- TIR domain-containing adaptor-inducing interferon-β
GenBank acession
- AB086380
Locus

19p13.3
Discovery year

2005-06-27
Entrez gene record

148022
Pubmed identfication
- 12539043
- 12471095
RefSeq identity
- NM_014261
Classification
- TIR domain containing
VEGA ID

OTTHUMG00000180248
Locus Specific Databases
- LRG_358

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325

Identity

HGNC:5760
Gene

IGKV1OR2-1
Long gene name

immunoglobulin kappa variable 1/OR2-1 (pseudogene)
Synonyms gene
- IGKVPZ1
- IGKV1OR-1
Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
Synonyms
- IGKV1/OR-1
- IGKV1/OR2-1
GenBank acession
- Z12367
Locus

2p11.1
Discovery year

2000-04-18
Entrez gene record

3531
Pubmed identfication
- 2853098
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000155081