TICAM (Toll-interleukin 1 Receptor Domain (TIR)-containing Adaptor Molecule-1, TRIF, Toll/IL-1 Receptor Domain-containing Adapter-inducing IFN-beta)
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Catalog number
MBS617043
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Price
Please ask
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Size
5x0.2 mL
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Products_type
Antibody
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Products_short_name
[TICAM]
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Products_name_syn
[Anti -TICAM (Toll-interleukin 1 Receptor Domain (TIR)-containing Adaptor Molecule-1, TRIF, Toll/IL-1 Receptor Domain-containing Adapter-inducing IFN-beta)]
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Other_names
[TIR domain-containing adapter molecule 2; TIR domain-containing adapter molecule 2; TIR domain-containing adapter molecule 2; OTTHUMP00000207407; cytoplasmic adaptor; TRIF-related adaptor molecule; NF-kappa-B-activating protein 502; toll-like receptor adaptor protein 3; putative NF-kappa-B-activating protein 502; toll/interleukin-1 receptor (TIR) domain-containing adapter protein; toll-like receptor adaptor molecule 2; Putative NF-kappa-B-activating protein 502; TRIF-related adapter molecule; Toll-like receptor adaptor protein 3; Toll/interleukin-1 receptor domain-containing protein]
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Other_gene_names
[TICAM2; TICAM2; TIRP; TRAM; TIRAP3; TICAM-2; MGC129876; MGC129877; TIRAP3; TIRP; TRAM]
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Clonality
Polyclonal
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Reactivity
Mouse
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Specificity
Recognizes mouse TICAM at ~66kD.
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Purity
Purified Purified
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Form
Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
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Storage_stability
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
ELISA (EL/EIA), Western Blot (WB)
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Gene
The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.
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Description
Whole adhesion and interacting molecules are present in lysates used as reference for ELISA quantification of these molecules and their subunits. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
IFNA1, IFNA10, IFNA6, IFNA21, IFNA5, IFNA16, TICAM1, IFNA14, IFNA8, IFNA7
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Short name
TICAM (Toll-interleukin 1 Receptor Domain (TIR)- Adaptor Molecule-1, TRIF, Toll/IL-1 Receptor Domain- Adapter- IFN-beta)
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Host
Rabbit
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Isotype
IgG
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Alternative name
TICAM (Toll-Interleukin 1 Receptor Domain (TIR)-containing Adaptor Molecule-1, TRIF, Toll/Interleukin-1 Receptor Domain-containing Adapter-inducing Interferon-b)
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Gene info
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Identity
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Gene
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Long gene name
interferon alpha 1
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Synonyms
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Synonyms name
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Locus
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Discovery year
1993-01-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interferon alpha 10
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Synonyms
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Locus
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Discovery year
1993-01-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interferon alpha 6
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Synonyms gene name
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Synonyms
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Locus
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Discovery year
1993-01-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interferon alpha 21
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Synonyms
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Synonyms name
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Locus
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Discovery year
1993-01-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interferon alpha 5
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Synonyms gene name
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Synonyms
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Locus
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Discovery year
1993-01-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interferon alpha 16
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Synonyms
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Locus
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Discovery year
1993-01-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
interferon alpha 14
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Synonyms gene name
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Synonyms
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Locus
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Discovery year
1993-01-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interferon alpha 8
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Synonyms gene name
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Synonyms
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Synonyms name
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Locus
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Discovery year
1993-01-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interferon alpha 7
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Synonyms
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Locus
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Discovery year
1993-01-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
The assay of INTERFERON-GAMMA released from lymphocytes after their exposure to a specific test antigen, to check for IMMUNOLOGIC MEMORY resulting from a previous exposure to the antigen. The amount of interferon-gamma released is usually assayed by an ENZYME-LINKED IMMUNOSORBENT ASSAY.
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Tree numbers
- E01.370.225.812.453
- E05.200.812.453
- E05.478.594.475
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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