TIMP-4, CT (TIMP4, Tissue Inhibitor of Metalloproteinases 4)

• Catalog number
  MBS643795
• Price
  Please ask
• Size
  5x0.05 mg

• Products_type
  Antibody
• Products_short_name
  [TIMP-4]
• Products_name_syn
  [Anti -TIMP-4, CT (TIMP4, Tissue Inhibitor of Metalloproteinases 4)]
• Other_names
  [TPA: metalloproteinase inhibitor 4; Metalloproteinase inhibitor 4; metalloproteinase inhibitor 4; TIMP-4; tissue inhibitor of metalloproteinase; tissue inhibitor of metalloproteinases 4; TIMP metallopeptidase inhibitor 4; Tissue inhibitor of metalloproteinases 4]
• Other_gene_names
  [TIMP4; TIMP4; TIMP-4]
• Clonality
  Polyclonal
• Reactivity
  Human, Mouse, Rat
• Specificity
  Recognizes human TIMP4. Species Crossreactivity: Mouse, rat.
• Purity
  Affinity Purified Purified by immunoaffinity chromatography.
• Form
  Supplied as a liquid in PBS, (without Mg2+, Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. 6

• Gene target
  TIMP-4   TIMP4   Tissue   Inhibitor   Metalloproteinases  
• Gene symbol
  TIMP4, TIMP1, MIR1302-4, PIRC18, PIRC16, SNORD114-4, IGKV2OR2-4, MIR941-4
• Short name
  TIMP-4, CT (TIMP4, Tissue Inhibitor of Metalloproteinases 4)
• Technique
  tissue, tissues
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  TIMP-4, CT (TIMP metallopeptidase inhibitor 4, Tissue suppressor on Metalloproteinases 4)
• Alternative technique
  tissues
• Alternative to gene target
  TIMP metallopeptidase inhibitor 4, TIMP4 and IDBG-18927 and ENSG00000157150 and 7079, metal ion binding, Extracellular, Timp4 and IDBG-179215 and ENSMUSG00000030317 and 110595, TIMP4 and IDBG-646400 and ENSBTAG00000020263 and 317694
• Tissue
  tissue

Gene info

• Identity
  HGNC:11823
• Gene
  TIMP4
• Long gene name
  TIMP metallopeptidase inhibitor 4
• Synonyms gene name
  • tissue inhibitor of metalloproteinase 4
• GenBank acession
  • U76456
• Locus
  3p25.2
• Discovery year
  1997-07-07
• Entrez gene record
  7079
• Pubmed identfication
  • 8939999
  • 9693046
• RefSeq identity
  • NM_003256
• Classification
  • Tissue inhibitor of metallopeptidases
• VEGA ID
  OTTHUMG00000129763

Gene info

• Identity
  HGNC:11820
• Gene
  TIMP1
• Long gene name
  TIMP metallopeptidase inhibitor 1
• Synonyms gene
  • TIMP
  • CLGI
• Synonyms gene name
  • tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor)
• Synonyms
  • EPO
• Locus
  Xp11.3
• Discovery year
  1986-01-01
• Entrez gene record
  7076
• RefSeq identity
  • NM_003254
• Classification
  • Tissue inhibitor of metallopeptidases
• VEGA ID
  OTTHUMG00000021447
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:35296
• Gene
  MIR1302-4
• Long gene name
  microRNA 1302-4
• Synonyms gene
  • MIRN1302-4
• Synonyms
  • hsa-mir-1302-4
• Locus
  2q33.3
• Discovery year
  2008-11-03
• Entrez gene record
  100302130
• RefSeq identity
  • NR_031633
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:37522
• Gene
  PIRC18
• Long gene name
  piwi-interacting RNA cluster 18
• Locus
  4
• Discovery year
  2009-11-05
• Entrez gene record
  100313906
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37520
• Gene
  PIRC16
• Long gene name
  piwi-interacting RNA cluster 16
• Locus
  4
• Discovery year
  2009-11-05
• Entrez gene record
  100313849
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:32992
• Gene
  SNORD114-4
• Long gene name
  small nucleolar RNA, C/D box 114-4
• Synonyms
  • 14q(II-4)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767580
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003196.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5809
• Gene
  IGKV2OR2-4
• Long gene name
  immunoglobulin kappa variable 2/OR2-4 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2/OR2-4
  • immunoglobulin kappa variable 2/OR2-4 pseudogene
• Synonyms
  • IGKV2/OR2-4
• GenBank acession
  • X51883
• Locus
  2q11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28858
• Pubmed identfication
  • 2111145
• Classification
  • Immunoglobulin kappa (IGK) orphons

Gene info

• Identity
  HGNC:33687
• Gene
  MIR941-4
• Long gene name
  microRNA 941-4
• Synonyms gene
  • MIRN941-4
• Synonyms
  • hsa-mir-941-4
• Locus
  20q13.33
• Discovery year
  2007-10-24
• Entrez gene record
  100126330
• RefSeq identity
  • NR_040032
• Classification
  • MicroRNAs

MeSH Data

• Name
  Tissue Fixation
• Concept
  Scope note: The technique of using FIXATIVES in the preparation of cytologic, histologic, or pathologic specimens for the purpose of maintaining the existing form and structure of all the constituent elements.
• Tree numbers
  • E01.370.225.500.620.760.720
  • E01.370.225.750.600.760.720
  • E05.200.500.620.760.720
  • E05.200.750.600.760.720
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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