TIMP2 (Metalloproteinase Inhibitor 2, CSC-21K, Tissue Inhibitor of Metalloproteinases 2, TIMP-2)

• Catalog number
  MBS628056
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [TIMP2]
• Products_name_syn
  [Anti -TIMP2 (Metalloproteinase Inhibitor 2, CSC-21K, Tissue Inhibitor of Metalloproteinases 2, TIMP-2)]
• Other_names
  [tissue inhibitor of metalloproteinase type 2; Metalloproteinase inhibitor 2; metalloproteinase inhibitor 2; TIMP-2; tissue inhibitor of metalloproteinase 2; tissue inhibitor of metalloproteinases 2; TIMP metallopeptidase inhibitor 2; Tissue inhibitor of metalloproteinases 2]
• Other_gene_names
  [Timp2; Timp2; MGC105282; Timp-2]
• Clonality
  Polyclonal
• Reactivity
  Human, Mouse, Rat
• Specificity
  Recognizes human TIMP-2. Species Cross-Reactivity: mouse, rat.
• Purity
  Affinity Purified Purified by immunoaffinity chromatography.
• Form
  Supplied as a liquid in PBS, pH 7.4, 50% glycerol.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  Western Blot (WB)
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. 6

• Gene target
  TIMP2   Metalloproteinase   Inhibitor   CSC-21K   Tissue   Inhibitor   Metalloproteinases   TIMP-2  
• Gene symbol
  TIMP2, TIMP1, MIR1289-2, MIR521-2, MIR509-2, MIR512-2, MIR7-2, MIR329-2, RNU6-2, KRTAP13-2
• Short name
  TIMP2 (Metalloproteinase Inhibitor 2, CSC-21K, Tissue Inhibitor of Metalloproteinases 2, TIMP-2)
• Technique
  tissue, tissues
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  TIMP metallopeptidase inhibitor 2 (Metalloproteinase suppressor 2, CSC-21K, Tissue suppressor on Metalloproteinases 2, TIMP-2)
• Alternative technique
  tissues
• Alternative to gene target
  TIMP metallopeptidase inhibitor 2, CSC-21K and DDC8, TIMP2 and IDBG-70963 and ENSG00000035862 and 7077, metal ion binding, Extracellular, Timp2 and IDBG-214632 and ENSMUSG00000017466 and 21858, BT.52974 and IDBG-642791 and ENSBTAG00000010899 and 282093
• Tissue
  tissue

Gene info

• Identity
  HGNC:11821
• Gene
  TIMP2
• Long gene name
  TIMP metallopeptidase inhibitor 2
• Synonyms gene name
  • tissue inhibitor of metalloproteinase 2
• Synonyms
  • CSC-21K
• Locus
  17q25.3
• Discovery year
  1992-06-18
• Entrez gene record
  7077
• Pubmed identfication
  • 1427908
• RefSeq identity
  • NM_003255
• Classification
  • Tissue inhibitor of metallopeptidases
• VEGA ID
  OTTHUMG00000154517

Gene info

• Identity
  HGNC:11820
• Gene
  TIMP1
• Long gene name
  TIMP metallopeptidase inhibitor 1
• Synonyms gene
  • TIMP
  • CLGI
• Synonyms gene name
  • tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor)
• Synonyms
  • EPO
• Locus
  Xp11.3
• Discovery year
  1986-01-01
• Entrez gene record
  7076
• RefSeq identity
  • NM_003254
• Classification
  • Tissue inhibitor of metallopeptidases
• VEGA ID
  OTTHUMG00000021447
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:35282
• Gene
  MIR1289-2
• Long gene name
  microRNA 1289-2
• Synonyms gene
  • MIRN1289-2
• Synonyms
  • hsa-mir-1289-2
• Locus
  5q31.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302134
• RefSeq identity
  • NR_031621
• Classification
  • MicroRNA MIR1289 family

Gene info

• Identity
  HGNC:32113
• Gene
  MIR521-2
• Long gene name
  microRNA 521-2
• Synonyms gene
  • MIRN521-2
• Synonyms
  • hsa-mir-521-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574481
• RefSeq identity
  • NR_030203
• Classification
  • MicroRNA MIR515 family

Gene info

• Identity
  HGNC:33641
• Gene
  MIR509-2
• Long gene name
  microRNA 509-2
• Synonyms gene
  • MIRN509-2
• Synonyms
  • hsa-mir-509-2
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126301
• RefSeq identity
  • NR_030586
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:32091
• Gene
  MIR512-2
• Long gene name
  microRNA 512-2
• Synonyms gene
  • MIRN512-2
• Synonyms
  • hsa-mir-512-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574459
• RefSeq identity
  • NR_030181
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:31639
• Gene
  MIR7-2
• Long gene name
  microRNA 7-2
• Synonyms gene
  • MIRN7-2
• Synonyms
  • hsa-mir-7-2
• Locus
  15q26.1
• Discovery year
  2004-04-23
• Entrez gene record
  407044
• RefSeq identity
  • NR_029606
• Classification
  • MicroRNA MIR7 family

Gene info

• Identity
  HGNC:32051
• Gene
  MIR329-2
• Long gene name
  microRNA 329-2
• Synonyms gene
  • MIRN329-2
• Synonyms
  • hsa-mir-329-2
• Locus
  14q32.31
• Discovery year
  2005-07-11
• Entrez gene record
  574409
• RefSeq identity
  • NR_029968
• Classification
  • MicroRNA MIR329 family

Gene info

• Identity
  HGNC:34270
• Gene
  RNU6-2
• Long gene name
  RNA, U6 small nuclear 2
• Synonyms
  • U6-2
• Locus
  19p13.3
• Discovery year
  2008-06-10
• Entrez gene record
  103625684
• Pubmed identfication
  • 12711679
• RefSeq identity
  • NR_125730
• Classification
  • Small nuclear RNAs

Gene info

• Identity
  HGNC:18923
• Gene
  KRTAP13-2
• Long gene name
  keratin associated protein 13-2
• Synonyms
  • KAP13-2
• GenBank acession
  • AP001708
• Locus
  21q22.11
• Discovery year
  2003-02-21
• Entrez gene record
  337959
• Pubmed identfication
  • 12359730
• Classification
  • Keratin associated proteins
• VEGA ID
  OTTHUMG00000057793

MeSH Data

• Name
  Tissue Embedding
• Concept
  Scope note: The technique of placing cells or tissue in a supporting medium so that thin sections can be cut using a microtome. The medium can be paraffin wax (PARAFFIN EMBEDDING) or plastics (PLASTIC EMBEDDING) such as epoxy resins.
• Tree numbers
  • E01.370.225.500.620.720
  • E01.370.225.750.600.720
  • E05.200.500.620.720
  • E05.200.750.600.720
• Qualifiers
  classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics

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