TCF-4 (T-cell Transcription Factor 4)

• Catalog number
  MBS601594
• Price
  Please ask
• Size
  5x0.2 mg

• Products_type
  Antibody
• Products_short_name
  [TCF-4]
• Products_name_syn
  [Anti -TCF-4 (T-cell Transcription Factor 4)]
• Other_names
  [transcription factor 4 isoform a; Transcription factor 4; transcription factor 4; ITF-2; SEF-2; TCF-4; OTTHUMP00000163567; OTTHUMP00000163568; SL3-3 enhancer factor 2; transcription factor 4, isoform B+; transcription factor 4, isoform B-; immunoglobulin transcription factor 2; class B basic helix-loop-helix protein 19; transcription factor 4; Class B basic helix-loop-helix protein 19; bHLHb19; Immunoglobulin transcription factor 2; ITF-2; SL3-3 enhancer factor 2]
• Other_gene_names
  [TCF4; TCF4; E2-2; ITF2; PTHS; SEF2; SEF2-1; SEF2-1A; SEF2-1B; bHLHb19; MGC149723; MGC149724; BHLHB19; ITF2; SEF2]
• Clonality
  Monoclonal
• Clone
  [0.T.149]
• Reactivity
  Human, Mouse
• Specificity
  Recognizes human TCF-4 at ~66kD. Species Crossreactivity: mouse
• Purity
  Affinity Purified Purified by Protein G affinity chromatography.
• Form
  Supplied as liquid in 0.1M Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05% sodium azide, 30% glycerol.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
• Description
  For cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.

• Gene target
  TCF-4   Transcription   Factor  
• Gene symbol
  TCF7L2, TCF4-AS2, TCF4-AS1, TCF7, MIR1302-4, PIRC18, TCF4, HGF
• Short name
  TCF-4 (T- Transcription Factor 4)
• Host
  Mouse
• Isotype
  IgG2a
• Alternative name
  TCF-4 (T-cellular Transcription Factor 4)
• Tissue
  cell

Gene info

• Identity
  HGNC:11641
• Gene
  TCF7L2
• Long gene name
  transcription factor 7 like 2
• Synonyms gene
  • TCF4
• Synonyms gene name
  • transcription factor 7-like 2 (T-cell specific, HMG-box)
• Synonyms
  • TCF-4
• GenBank acession
  • X62871
• Locus
  10q25.2-q25.3
• Discovery year
  1998-01-20
• Entrez gene record
  6934
• Pubmed identfication
  • 1741298
• RefSeq identity
  • NM_030756
• Classification
  • TCF/LEF transcription factor family
  • Wnt enhanceosome complex
• VEGA ID
  OTTHUMG00000019070

Gene info

• Identity
  HGNC:51643
• Gene
  TCF4-AS2
• Long gene name
  TCF4 antisense RNA 2
• Locus
  18q21.2
• Discovery year
  2015-04-09
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000179869

Gene info

• Identity
  HGNC:51642
• Gene
  TCF4-AS1
• Long gene name
  TCF4 antisense RNA 1
• Synonyms
  • MIR4529HG
• Synonyms name
  • MIR4529 host gene
• Locus
  18q21.2
• Discovery year
  2015-04-09
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000179868

Gene info

• Identity
  HGNC:11639
• Gene
  TCF7
• Long gene name
  transcription factor 7
• Synonyms gene name
  • transcription factor 7 (T-cell specific, HMG-box)
• Synonyms
  • TCF-1
• Synonyms name
  • T-cell-factor-7
• GenBank acession
  • Z47362
• Locus
  5q31.1
• Discovery year
  1991-08-18
• Entrez gene record
  6932
• RefSeq identity
  • NM_201634
• Classification
  • TCF/LEF transcription factor family
  • Wnt enhanceosome complex
• VEGA ID
  OTTHUMG00000129124

Gene info

• Identity
  HGNC:35296
• Gene
  MIR1302-4
• Long gene name
  microRNA 1302-4
• Synonyms gene
  • MIRN1302-4
• Synonyms
  • hsa-mir-1302-4
• Locus
  2q33.3
• Discovery year
  2008-11-03
• Entrez gene record
  100302130
• RefSeq identity
  • NR_031633
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:37522
• Gene
  PIRC18
• Long gene name
  piwi-interacting RNA cluster 18
• Locus
  4
• Discovery year
  2009-11-05
• Entrez gene record
  100313906
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:11634
• Gene
  TCF4
• Long gene name
  transcription factor 4
• Synonyms
  • SEF2-1B
  • ITF2
  • bHLHb19
  • E2-2
• Synonyms name
  • SL3-3 enhancer factor 2
  • class B basic helix-loop-helix protein 19
  • immunoglobulin transcription factor 2
• GenBank acession
  • M74719
• Locus
  18q21.2
• Discovery year
  1990-10-16
• Entrez gene record
  6925
• Pubmed identfication
  • 9302263
  • 2308860
• RefSeq identity
  • NM_003199
• Classification
  • Basic helix-loop-helix proteins
• VEGA ID
  OTTHUMG00000132713
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:4893
• Gene
  HGF
• Long gene name
  hepatocyte growth factor
• Synonyms gene
  • DFNB39
• Synonyms gene name
  • deafness, autosomal recessive 39
  • hepatocyte growth factor (hepapoietin A; scatter factor)
• Synonyms
  • SF
  • F-TCF
  • HGFB
  • HPTA
• Synonyms name
  • hepatopoietin A
  • fibroblast-derived tumor cytotoxic factor
  • scatter factor
  • lung fibroblast-derived mitogen
• Locus
  7q21.11
• Discovery year
  1991-06-07
• Entrez gene record
  3082
• Pubmed identfication
  • 1837206
  • 19576567
• RefSeq identity
  • NM_000601
• VEGA ID
  OTTHUMG00000023804

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