SPINK1 (Pancreatic Secretory Trypsin Inhibitor, Serine Protease Inhibitor Kazal-type 1, Tumor-associated Trypsin Inhibitor, TATI, PSTI)
-
Catalog numberMBS644689
-
PricePlease ask
-
Size0.1 mg
-
-
Products_typeAntibody
-
Products_short_name[SPINK1]
-
Products_name_syn[Anti -SPINK1 (Pancreatic Secretory Trypsin Inhibitor, Serine Protease Inhibitor Kazal-type 1, Tumor-associated Trypsin Inhibitor, TATI, PSTI)]
-
ClonalityMonoclonal
-
Clone[4D4]
-
ReactivityHuman
-
SpecificityRecognizes human SPINK1.
-
PurityAffinity Purified Purified by Protein A affinity chromatography.
-
FormSupplied as a liquid in PBS, pH 7.2.
-
Storage_stabilityMay be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
-
Tested_applicationELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
-
DescriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+ 3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.
-
Gene target
-
Gene symbolSPINK1
-
Short nameSPINK1 (Pancreatic Secretory Trypsin Inhibitor, Serine Protease Inhibitor Kazal- 1, Tumor-associated Trypsin Inhibitor, TATI, PSTI)
-
HostMouse
-
IsotypeIgG2a,k
-
Alternative nameSPINK1 (Pancreatic Secretory Trypsin suppressor, Serine Protease suppressor Kazal-classification 1, Tumor-associated Trypsin suppressor, TATI, PSTI)
-
Tissuetumor
-
Gene info
-
Identity
-
Gene
-
Long gene nameserine peptidase inhibitor Kazal type 1
-
Synonyms gene name
- serine protease inhibitor, Kazal type 1
-
Synonyms
-
Locus
-
Discovery year1988-06-27
-
Entrez gene record
-
RefSeq identity
-
Classification
- Serine peptidase inhibitors, Kazal type
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
-
Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data