SPINK1 (Pancreatic Secretory Trypsin Inhibitor, Serine Protease Inhibitor Kazal-type 1, Tumor-associated Trypsin Inhibitor, TATI, PSTI)

• Catalog number
  MBS6005549
• Price
  Please ask
• Size
  0,05 mg

• Other size
  please contact us to order other different size
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+ 3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.

• Gene target
  SPINK1   Pancreatic   Secretory   Trypsin   Inhibitor   Serine   Protease   Inhibitor   Kazal   Tumor-associated   Trypsin   Inhibitor   TATI   PSTI  
• Gene symbol
  SPINK1
• Short name
  SPINK1 (Pancreatic Secretory Trypsin Inhibitor, Serine Protease Inhibitor Kazal- 1, Tumor-associated Trypsin Inhibitor, TATI, PSTI)
• Alternative name
  SPINK1 (Pancreatic Secretory Trypsin suppressor, Serine Protease suppressor Kazal-classification 1, Tumor-associated Trypsin suppressor, TATI, PSTI)
• Tissue
  tumor

Gene info

• Identity
  HGNC:11244
• Gene
  SPINK1
• Long gene name
  serine peptidase inhibitor Kazal type 1
• Synonyms gene name
  • serine protease inhibitor, Kazal type 1
• Synonyms
  • Spink3
  • PCTT
  • PSTI
  • TATI
• Locus
  5q32
• Discovery year
  1988-06-27
• Entrez gene record
  6690
• RefSeq identity
  • NM_003122
• Classification
  • Serine peptidase inhibitors, Kazal type
• VEGA ID
  OTTHUMG00000129730

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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