Recombinant RAR Related Orphan Receptor Alpha (RORa)

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Description

The Recombinant RAR Orphan Receptor Alpha (RORa) is a α- or alpha protein sometimes glycoprotein present in blood. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

RAR Related Orphan Receptor Alpha RORa
Gene symbol

RARA, RAB40B, PRAM1, RAB40A
Short name

Recombinant RAR Orphan Receptor Alpha (RORa)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Alternative name

Rec. RAR Related Orphan Receptor a (RAR-related orphan receptor A)
Alternative technique

rec
Alternative to gene target

RAR-related orphan receptor A, NR1F1 and ROR1 and ROR2 and ROR3 and RZR-ALPHA and RZRA, RORA and IDBG-14920 and ENSG00000069667 and 6095, direct ligand regulated sequence-specific DNA binding transcription factor activity, nuclei, Rora and IDBG-181478 and ENSMUSG00000032238 and 19883, RORA and IDBG-646570 and ENSBTAG00000015904 and 535597,790889

Identity

HGNC:18284
Gene

RAB40B
Long gene name

RAB40B, member RAS oncogene family
Synonyms
- SEC4L
- RAR
GenBank acession
- U05227
Locus

17q25.3
Discovery year

2002-02-22
Entrez gene record

10966
Pubmed identfication
- 11697911
Classification
- RAB, member RAS oncogene GTPases
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000177806

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data