Recombinant RAR Related Orphan Receptor Alpha (RORa)

• Catalog number
  RPD947Hu01
• Price
  Please ask
• Size
  428

• Source
  Prokaryotic expression
• Predicted Molecular Mass KD
  31.0kDa
• Accurate Molecular Mass KD
  NA
• Organism species
  Homo sapiens (Human)
• Item Name
  RAR Related Orphan Receptor Alpha
• Alternative Names
  ROR1; ROR2; NR1F1; ROR3; RZRA; Nuclear receptor subfamily 1 group F member 1; Retinoid-related orphan receptor-alpha
• Research Area
  Tumor immunity;
• Buffer Formulation
  PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Traits
  Freeze-dried powder
• Purity
  ≥ 98%
• Protein length
  Gln164~Met401
• Tag
  two N-terminal Tags, His-tag and T7-tag
• Expression System
  Prokaryotic expression
• Application
  Positive Control; Immunogen; SDS-PAGE; WB.
• Manual link
• Description
  The Recombinant RAR Orphan Receptor Alpha (RORa) is a α- or alpha protein sometimes glycoprotein present in blood. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  RAR   Related   Orphan   Receptor   Alpha   RORa  
• Gene symbol
  RARA, RAB40B, PRAM1, RAB40A
• Short name
  Recombinant RAR Orphan Receptor Alpha (RORa)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E.coli
• Species
  Homo sapiens (Human)
• Alternative name
  Rec. RAR Related Orphan Receptor a (RAR-related orphan receptor A)
• Alternative technique
  rec
• Alternative to gene target
  RAR-related orphan receptor A, NR1F1 and ROR1 and ROR2 and ROR3 and RZR-ALPHA and RZRA, RORA and IDBG-14920 and ENSG00000069667 and 6095, direct ligand regulated sequence-specific DNA binding transcription factor activity, nuclei, Rora and IDBG-181478 and ENSMUSG00000032238 and 19883, RORA and IDBG-646570 and ENSBTAG00000015904 and 535597,790889

Gene info

• Identity
  HGNC:9864
• Gene
  RARA
• Long gene name
  retinoic acid receptor alpha
• Synonyms gene name
  • retinoic acid receptor, alpha
• Synonyms
  • RAR
  • NR1B1
• GenBank acession
  • X06538
• Locus
  17q21.2
• Discovery year
  1988-06-09
• Entrez gene record
  5914
• Pubmed identfication
  • 2825036
  • 8244378
• Classification
  • Retinoic acid receptors
• VEGA ID
  OTTHUMG00000133328
• Locus Specific Databases
  • LRG_1070

Gene info

• Identity
  HGNC:18284
• Gene
  RAB40B
• Long gene name
  RAB40B, member RAS oncogene family
• Synonyms
  • SEC4L
  • RAR
• GenBank acession
  • U05227
• Locus
  17q25.3
• Discovery year
  2002-02-22
• Entrez gene record
  10966
• Pubmed identfication
  • 11697911
• Classification
  • RAB, member RAS oncogene GTPases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000177806

Gene info

• Identity
  HGNC:30091
• Gene
  PRAM1
• Long gene name
  PML-RARA regulated adaptor molecule 1
• Synonyms
  • PML-RAR
• GenBank acession
  • BC028012
• Locus
  19p13.2
• Discovery year
  2005-07-04
• Entrez gene record
  84106
• Pubmed identfication
  • 11301322
  • 15572693
• RefSeq identity
  • NM_032152
• VEGA ID
  OTTHUMG00000167924

Gene info

• Identity
  HGNC:18283
• Gene
  RAB40A
• Long gene name
  RAB40A, member RAS oncogene family
• Synonyms
  • RAR2A
  • Rar-2
• GenBank acession
  • AF132748
• Locus
  Xq22.2
• Discovery year
  2002-02-22
• Entrez gene record
  142684
• Pubmed identfication
  • 11697911
• Classification
  • RAB, member RAS oncogene GTPases
• VEGA ID
  OTTHUMG00000022100
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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