Recombinant Pig Leptin receptor (LEPR), partial
-
Catalog number
MBS1256655
-
Price
Please ask
-
Size
INQUIRE
-
-
Products_type
Recombinant Protein
-
Products_short_name
[Leptin receptor (LEPR)]
-
Other_names
[leptin receptor; Leptin receptor; leptin receptor; OB receptor; OB-R; CD_antigen: CD295]
-
Products_gene_name
[LEPR]
-
Other_gene_names
[LEPR; LEPR; OBR; LEP-R; OB-R]
-
Purity
>85% (SDS-PAGE)
-
Form
Lyophilized or liquid (Format to be determined during the manufacturing process)
-
Storage_stability
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
-
Gene
Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.
-
About
Pigs and the smaller guinea pigs are frequent used as models for humans.
-
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
Source
Recombinants or rec. proteins
-
Group
recombinants
-
Gene target
-
Gene symbol
LEPR
-
Short name
Recombinant Leptin receptor (LEPR), partial
-
Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
-
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
-
Species
Pig, Pigs and Guinea pigs
-
Alternative name
Rec. swine Leptin receptor (leptin receptor), partial
-
Alternative technique
rec
-
Alternative to gene target
leptin receptor, CD295 and LEP-R and LEPRD and OB-R and OBR, LEPR and IDBG-99469 and ENSG00000116678 and 3953, identical protein binding, Extracellular, Lepr and IDBG-167734 and ENSMUSG00000057722 and 16847, LEPR and IDBG-638266 and ENSBTAG00000005910 and 497205,785813
-
Gene info
-
Identity
-
Gene
-
Long gene name
leptin receptor
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year
1996-05-09
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- CD molecules
- Immunoglobulin like domain containing
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
-
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products