Leptin Receptor

• Catalog number
  GT15059
• Price
  Please ask
• Size
  100 ug

• Dilutions
  NA
• Immunogen
  Purified, NS0-derived, recombinant human Leptin R (rhLeptin R) extracellular domain.
• Storage
  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Storage Location
  Frozen (Polar Packs)
• Entrez
  3953
• UniProt
  P48357
• RRID
  AB_2737190
• Applications
  WB, IHC, E
• Types
  Goat IgG
• Format A
  Affinity Purified
• Format B
  liquid
• Datasheets
• Gene
  Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Leptin   Receptor  
• Gene symbol
  LEPR, LEPROT, LEPROTL1
• Short name
  Leptin Receptor
• Species
  Human
• Alternative name
  Leptin Receptor

Gene info

• Identity
  HGNC:6554
• Gene
  LEPR
• Long gene name
  leptin receptor
• Synonyms
  • OBR
  • CD295
• GenBank acession
  • U43168
• Locus
  1p31.3
• Discovery year
  1996-05-09
• Entrez gene record
  3953
• Pubmed identfication
  • 8548812
  • 8812446
• RefSeq identity
  • NM_002303
• Classification
  • CD molecules
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000009115
• Locus Specific Databases
  • LRG_283

Gene info

• Identity
  HGNC:29477
• Gene
  LEPROT
• Long gene name
  leptin receptor overlapping transcript
• Synonyms
  • OBRGRP
  • OB-RGRP
  • VPS55
  • FLJ90360
• Synonyms name
  • leptin receptor gene related protein
  • endospanin-1
  • endospanin
• GenBank acession
  • Y12670
• Locus
  1p31.3
• Discovery year
  2004-11-16
• Entrez gene record
  54741
• Pubmed identfication
  • 9207021
  • 21454707
• RefSeq identity
  • NM_017526
• VEGA ID
  OTTHUMG00000009065

Gene info

• Identity
  HGNC:6555
• Gene
  LEPROTL1
• Long gene name
  leptin receptor overlapping transcript like 1
• Synonyms
  • my047
  • Vps55
• Synonyms name
  • endospanin-2
• GenBank acession
  • AF063605
• Locus
  8p12
• Discovery year
  2000-06-15
• Entrez gene record
  23484
• Pubmed identfication
  • 11342119
• VEGA ID
  OTTHUMG00000163820

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