Recombinant Human soluble CD40 Ligand/TRAP His Tag

• Catalog number
  MBS143564
• Price
  Please ask
• Size
  0.02 mg

• Products_type
  Recombinant Protein
• Products_short_name
  [soluble CD40 Ligand/TRAP]
• Products_name_syn
  [sCD40L Human, His; soluble CD40 Ligand/TRAP Human Recombinant, His Tag; CD40-L; Tumor necrosis factor ligand superfamily member 5; TNF-related activation protein; TRAP; T cell antigen Gp39; CD154 antigen; sCD40; IGM; IMD3; HIGM1; T-BAM; TNFSF5; hCD40L; CD40LG; sCD40L His]
• Other_names
  [CD40 ligand; CD40 ligand; CD40 ligand; CD40 antigen ligand; CD40-L; T-B cell-activating molecule; T-cell antigen Gp39; TNF-related activation protein; tumor necrosis factor (ligand) superfamily member 5; CD40 ligand; T-cell antigen Gp39; TNF-related activation protein; TRAP; Tumor necrosis factor ligand superfamily member 5; CD_antigen: CD154Cleaved into the following 2 chains:CD40 ligand, membrane form; CD40 ligand, soluble form]
• Products_gene_name
  [sCD40L]
• Other_gene_names
  [CD40LG; CD40LG; IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L; CD40L; TNFSF5; TRAP; CD40-L; TRAP]
• Purity
  Greater than 95.0% as determined by SDS-PAGE.
• Form
  The CD40LG solution (0.5mg/ml) 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 40% glycerol and 0.2M NaCl.
• Storage_stability
  Store at 4°C if entire vial will be used within 2-4 weeks. Store,frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
• Conjugation
  histidine
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Description
  FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  soluble   CD40   Ligand/TRAP   His   Tag  
• Gene symbol
  ACP5, CD40, TGFBRAP1, CD40LG, SCYL1
• Short name
  Recombinant soluble CD40 Ligand/TRAP His Tag
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Host
  Escherichia Coli
• Label
  His
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens soluble CD40 molecule, tumor necrosis factor receptor superfamily member 5 Ligand/TRAP histidine detection labelled
• Alternative technique
  rec
• Alternative to gene target
  CD40 molecule, TNF receptor superfamily member 5, Bp50 and CDW40 and p50 and TNFRSF5, CD40 and IDBG-78904 and ENSG00000101017 and 958, ubiquitin protein ligase binding, Extracellular, Cd40 and IDBG-212533 and ENSMUSG00000017652 and 21939, BT.42498 and IDBG-643036 and ENSBTAG00000020736 and 286849

Gene info

• Identity
  HGNC:124
• Gene
  ACP5
• Long gene name
  acid phosphatase 5, tartrate resistant
• Synonyms
  • TRAP
  • HPAP
• Synonyms name
  • tartrate-resistant acid phosphatase
  • human purple acid phosphatase
• GenBank acession
  • X14618
• Locus
  19p13.2
• Discovery year
  1989-02-23
• Entrez gene record
  54
• Pubmed identfication
  • 8449511
  • 2338077
• Classification
  • Acid phosphatases
• VEGA ID
  OTTHUMG00000182036
• Locus Specific Databases
  • LRG_1218

Gene info

• Identity
  HGNC:11919
• Gene
  CD40
• Long gene name
  CD40 molecule
• Synonyms gene
  • TNFRSF5
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 5
  • CD40 molecule, TNF receptor superfamily member 5
• Synonyms
  • p50
  • Bp50
• GenBank acession
  • X60592
• Locus
  20q13.12
• Discovery year
  1993-08-27
• Entrez gene record
  958
• Pubmed identfication
  • 7687385
  • 2998589
• RefSeq identity
  • NM_001250
• Classification
  • CD molecules
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000033053
• Locus Specific Databases
  • CD40base: Mutation registry for CD40 deficiency (previously known as TNFRSF5base)
  • LRG_40

Gene info

• Identity
  HGNC:16836
• Gene
  TGFBRAP1
• Long gene name
  transforming growth factor beta receptor associated protein 1
• Synonyms gene name
  • transforming growth factor, beta receptor associated protein 1
• Synonyms
  • TRAP-1
  • TRAP1
  • VPS3
• Synonyms name
  • VPS3 CORVET complex subunit
• GenBank acession
  • AF022795
• Locus
  2q12.1-q12.2
• Discovery year
  2003-02-11
• Entrez gene record
  9392
• Pubmed identfication
  • 9545258
  • 11278302
  • 26463206
• RefSeq identity
  • NM_004257
• Classification
  • CORVET complex
• VEGA ID
  OTTHUMG00000130809

Gene info

• Identity
  HGNC:11935
• Gene
  CD40LG
• Long gene name
  CD40 ligand
• Synonyms gene
  • HIGM1
  • IMD3
  • TNFSF5
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome)
• Synonyms
  • CD40L
  • TRAP
  • gp39
  • hCD40L
  • CD154
• Synonyms name
  • CD40 antigen ligand
  • tumor necrosis factor (ligand) superfamily member 5
  • T-B cell-activating molecule
  • TNF-related activation protein
  • hyper-IgM syndrome
• GenBank acession
  • X67878
• Locus
  Xq26.3
• Discovery year
  1989-06-30
• Entrez gene record
  959
• Pubmed identfication
  • 1427881
  • 7678782
• RefSeq identity
  • NM_000074
• Classification
  • CD molecules
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000022512
• Locus Specific Databases
  • CD40Lbase: Mutation registry for X-linked Hyper-IgM syndrome
  • Global Variome shared LOVD
  • LRG_141

Gene info

• Identity
  HGNC:14372
• Gene
  SCYL1
• Long gene name
  SCY1 like pseudokinase 1
• Synonyms gene
  • NTKL
• Synonyms gene name
  • N-terminal kinase-like
  • SCY1-like 1 (S. cerevisiae)
  • SCY1-like, kinase-like 1
• Synonyms
  • HT019
  • P105
  • GKLP
  • NKTL
  • TAPK
  • TRAP
  • TEIF
  • MGC78454
• Synonyms name
  • teratoma-associated tyrosine kinase
  • telomerase transcriptional elements-interacting factor
  • telomerase regulation-associated protein
• GenBank acession
  • AF225424
• Locus
  11q13.1
• Discovery year
  2001-01-16
• Entrez gene record
  57410
• Pubmed identfication
  • 11118629
• RefSeq identity
  • NM_020680
• Classification
  • Armadillo like helical domain containing
  • SCY1 like pseudokinases
• VEGA ID
  OTTHUMG00000166325

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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