Mouse soluble CD40 Ligand (mSCD40L)

• Catalog number
  MBS400004
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Active Protein
• Products_short_name
  [soluble CD40 Ligand]
• Products_name_syn
  [Mouse soluble CD40 Ligand (hsCD40-L)]
• Other_names
  [CD40 ligand; CD40 ligand; CD40 ligand; CD40 antigen ligand; CD40-L; T-B cell-activating molecule; T-cell antigen Gp39; TNF-related activation protein; tumor necrosis factor (ligand) superfamily member 5; CD40 ligand; T-cell antigen Gp39; TNF-related activation protein; TRAP]
• Products_gene_name
  [mSCD40L]
• Other_gene_names
  [CD40LG; CD40LG; IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L; CD40L; TNFSF5; TRAP; CD40-L; TRAP]
• Purity
  Greater than 98.0% as determined by:(a) Analysis by RP-HPLC.(b) Anion-exchange FPLC.(c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.
• Form
  Sterile Filtered White lyophilized (freeze-dried) powder.
• Storage_stability
  Lyophilized CD40L although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution CD40L should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
• Description
  FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  soluble   CD40   Ligand   mSCD40L  
• Gene symbol
  CD40
• Short name
  Mouse soluble CD40 Ligand (mSCD40L)
• Technique
  Mouse, mouses
• Host
  mouse
• Species
  Mouse, Mouses
• Alternative name
  Mouse soluble CD40 molecule, tumor necrosis factor receptor superfamily member 5 Ligand (mSCD40L)
• Alternative technique
  murine
• Alternative to gene target
  CD40 molecule, TNF receptor superfamily member 5, Bp50 and CDW40 and p50 and TNFRSF5, CD40 and IDBG-78904 and ENSG00000101017 and 958, ubiquitin protein ligase binding, Extracellular, Cd40 and IDBG-212533 and ENSMUSG00000017652 and 21939, BT.42498 and IDBG-643036 and ENSBTAG00000020736 and 286849

Gene info

• Identity
  HGNC:11919
• Gene
  CD40
• Long gene name
  CD40 molecule
• Synonyms gene
  • TNFRSF5
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 5
  • CD40 molecule, TNF receptor superfamily member 5
• Synonyms
  • p50
  • Bp50
• GenBank acession
  • X60592
• Locus
  20q13.12
• Discovery year
  1993-08-27
• Entrez gene record
  958
• Pubmed identfication
  • 7687385
  • 2998589
• RefSeq identity
  • NM_001250
• Classification
  • CD molecules
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000033053
• Locus Specific Databases
  • CD40base: Mutation registry for CD40 deficiency (previously known as TNFRSF5base)
  • LRG_40

MeSH Data

• Name
  CD4 Lymphocyte Count
• Concept
  Scope note: The number of CD4-POSITIVE T-LYMPHOCYTES per unit volume of BLOOD. Determination requires the use of a fluorescence-activated flow cytometer.
• Tree numbers
  • E01.370.225.500.195.107.595.500.150
  • E01.370.225.625.107.595.500.150
  • E05.200.500.195.107.595.500.150
  • E05.200.625.107.595.500.150
  • E05.242.195.107.595.500.150
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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