Recombinant Human Methyl CpG Binding Protein 2

• Catalog number
  MBS144922
• Price
  Please ask
• Size
  5x0.1 mg

• Products_type
  Recombinant Protein
• Products_short_name
  [Methyl CpG Binding Protein 2]
• Products_name_syn
  [MECP2 Human; Methyl CpG Binding Protein 2 Human Recombinant; Methyl CpG binding protein 2 (Rett syndrome); MeCp-2 protein; AUTSX3; MRX16; MRX79; MRXS13; MRXSL; PPMX; RTT; Mental retardation; X-linked 16; DKFZp686A24160]
• Other_names
  [methyl-CpG-binding protein 2 isoform 2; Methyl-CpG-binding protein 2; methyl-CpG-binding protein 2; meCp-2 protein; methyl CpG binding protein 2]
• Products_gene_name
  [MECP2]
• Other_gene_names
  [MECP2; MECP2; RS; RTS; RTT; PPMX; MRX16; MRX79; MRXSL; AUTSX3; MRXS13; MeCp-2 protein; MeCp2]
• Purity
  Greater than 80% as determined by SDS-PAGE.
• Form
  The MECP2 solution (0.45mg/ml) contains 50mM Tris, 135mM NaCl, 20% Glycerol, pH 7.5 and 200 ug/ml DYKDDDDK peptide.Sterile Filtered colorless solution.
• Storage_stability
  MECP2 although stable 4 degree C for 4 weeks, should be stored below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Description
  A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Methyl   CpG   Binding   Protein  
• Gene symbol
  MBD2, MECP2, MBD3L2
• Short name
  Recombinant Methyl CpG Binding Protein 2
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  Mammalian system, 293 cells
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Methyl CpG Binding Protein 2
• Alternative technique
  rec

Gene info

• Identity
  HGNC:6917
• Gene
  MBD2
• Long gene name
  methyl-CpG binding domain protein 2
• GenBank acession
  • AF072242
• Locus
  18q21.2
• Discovery year
  1999-01-11
• Entrez gene record
  8932
• Pubmed identfication
  • 9774669
  • 10441743
• RefSeq identity
  • NM_003927
• Classification
  • Small nucleolar RNA protein coding host genes
  • NuRD complex subunits
  • Methyl-CpG binding domain containing
• VEGA ID
  OTTHUMG00000132705

Gene info

• Identity
  HGNC:6990
• Gene
  MECP2
• Long gene name
  methyl-CpG binding protein 2
• Synonyms gene
  • RTT
  • MRX16
  • MRX79
• Synonyms gene name
  • mental retardation, X-linked 16
  • mental retardation, X-linked 79
  • Rett syndrome
  • methyl CpG binding protein 2 (Rett syndrome)
  • methyl CpG binding protein 2
• GenBank acession
  • AF158180
• Locus
  Xq28
• Discovery year
  1996-09-03
• Entrez gene record
  4204
• Pubmed identfication
  • 1606614
  • 10508514
• RefSeq identity
  • NM_004992
• Classification
  • Methyl-CpG binding domain containing
• VEGA ID
  OTTHUMG00000024229
• Locus Specific Databases
  • RettBASE
  • Global Variome shared LOVD
  • LRG_764

Gene info

• Identity
  HGNC:18532
• Gene
  MBD3L2
• Long gene name
  methyl-CpG binding domain protein 3 like 2
• GenBank acession
  • AF503919
• Locus
  19p13.2
• Discovery year
  2002-04-29
• Entrez gene record
  125997
• RefSeq identity
  • NM_144614
• VEGA ID
  OTTHUMG00000181975

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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