MBD1 (Methyl CpG Binding Protein 1, MeCP1, CXXC3, MeCP1 Complex, Methyl CpG Binding Domain Protein 1, Methyl CpG Binding Protein MBD1, Protein Containing Methyl CpG Binding Domain 1, PCM1, Regulator of Fibroblast Growth Factor 2 (FGF 2) Transcription, RFT

  • Catalog number
    MBS600629
  • Price
    Please ask
  • Size
    0.1 mg
  • Products_type
    Antibody
  • Products_short_name
    [MBD1]
  • Products_name_syn
    [Anti -MBD1 (Methyl CpG Binding Protein 1, MeCP1, CXXC3, MeCP1 Complex, Methyl CpG Binding Domain Protein 1, Methyl CpG Binding Protein MBD1, Protein Containing Methyl CpG Binding Domain 1, PCM1, Regulator of Fibroblast Growth Factor 2 (FGF 2) Transcription, RFT]
  • Other_names
    [MBD1]
  • Clonality
    Monoclonal
  • Clone
    [8L709]
  • Reactivity
    Human
  • Specificity
    This monoclonal antibody can be used for detection of MBD1, isoform 1, a 605 amino acid protein. In HeLa, a 70kD band is observed. Species Crossreactivity: Human.
  • Purity
    Affinity Purified Purified by immunoaffinity chromatography.
  • Form
    Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
  • Storage_stability
    May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
  • Tested_application
    Western Blot (WB)
  • Description
    Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed, The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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