Recombinant Human IGF-Like Family Receptor 1
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Catalog number
MBS145529
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Price
Please ask
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Size
0.01 mg
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Products_type
Recombinant Protein
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Products_short_name
[IGF-Like Family Receptor 1]
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Products_name_syn
[IGFLR1 Human; IGF-Like Family Receptor 1 Human Recombinant; TMEM149; U2AF1L4; IGF-like family receptor 1; Transmembrane protein 149; U2 small nuclear RNA auxiliary factor 1-like 4; IGFLR1]
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Other_names
[IGF-like family receptor 1; IGF-like family receptor 1; IGF-like family receptor 1; U2 small nuclear RNA auxiliary factor 1-like 4; U2(RNU2) small nuclear RNA auxiliary factor 1-like 4; transmembrane protein 149; IGF-like family receptor 1; Transmembrane protein 149; U2 small nuclear RNA auxiliary factor 1-like 4]
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Products_gene_name
[IGFLR1]
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Other_gene_names
[IGFLR1; IGFLR1; TMEM149; U2AF1L4; TMEM149; U2AF1L4]
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Purity
Greater than 90% as determined by SDS-PAGE.
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Form
The IGFLR1 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 7.5), 0.2M NaCl, 50% glycerol and 2mM DTT.Sterile Filtered colorless solution.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Description
IGF-I, IGF-II, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
RXFP3, RXFP1, IGFLR1
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Short name
Recombinant IGF-Like Family Receptor 1
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Technique
Recombinant, IGF, igfs, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
E Coli
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Species
Human, Humans
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Alternative name
Rec. H. sapiens IGF-Like family Receptor 1
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Alternative technique
rec, igfs
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Gene info
Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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